Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal
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DOI: 10.1126/sciadv.aba4353
Abstract: PTPRS-targeted FLS-directed therapy synergizes with TNF inhibition in therapy of arthritis. Fibroblast-like synoviocytes (FLS) are joint-lining cells that promote rheumatoid arthritis (RA) pathology. Current disease-modifying antirheumatic agents (DMARDs) operate through systemic immunosuppression. FLS-targeted approaches could… read more here.
Keywords: synergizes tnf; tnf inhibition; therapy; arthritis ... See more keywords
Effects of Etanercept on TNF-α Inhibition in Rats with Adenine-Induced Chronic Kidney Disease
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DOI: 10.1155/2022/4970753
Abstract: Introduction Chronic kidney disease (CKD) constitutes a chronic inflammatory state associated with an increase in inflammatory mediators and profibrotic molecules such as tumor necrosis factor-α (TNF-α). Etanercept (ETA) is a TNF inhibitor widely used in… read more here.
Keywords: inhibition; adenine induced; tnf; chronic kidney ... See more keywords