Microglia modulate TNFα-mediated synaptic plasticity.
Sign Up to like & getrecommendations! Published in 2023 at "Glia"
DOI: 10.1002/glia.24383
Abstract: The pro-inflammatory cytokine tumor necrosis factor α (TNFα) tunes the capacity of neurons to express synaptic plasticity. It remains, however, unclear how TNFα mediates synaptic positive (=change) and negative (=stability) feedback mechanisms. We assessed effects… read more here.
Keywords: tnf; mediated synaptic; plasticity; tnf mediated ... See more keywords
MiR-18a-downregulated RORA inhibits the proliferation and tumorigenesis of glioma using the TNF-α-mediated NF-κB signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2020.102651
Abstract: Background Glioma has a poor prognosis, and is the most common primary and lethal primary malignant tumor in the central nervous system. Retinoic acid receptor-related orphan receptor A (RORA) is a member of the ROR… read more here.
Keywords: glioma; tnf mediated; proliferation tumorigenesis; tumorigenesis glioma ... See more keywords
System level modeling and analysis of TNF-α mediated sphingolipid signaling pathway in neurological disorders for the prediction of therapeutic targets
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.872421
Abstract: Sphingomyelin (SM) belongs to a class of lipids termed sphingolipids. The disruption in the sphingomyelin signaling pathway is associated with various neurodegenerative disorders. TNF-α, a potent pro-inflammatory cytokine generated in response to various neurological disorders… read more here.
Keywords: signaling pathway; analysis tnf; neurological disorders; analysis ... See more keywords
TNF-α-Mediated Endothelial Cell Apoptosis Is Rescued by Hydrogen Sulfide
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12030734
Abstract: Highlights Hydrogen sulfide ameliorates TNF-α mediated endothelial dysfunction in human endothelial cells by regulating the intrinsic apoptosis pathway. Beneficial effects of hydrogen sulfide against TNF-α mediated apoptosis in endothelial cells are associated with S-sulfhydration of… read more here.
Keywords: hydrogen sulfide; mediated endothelial; tnf mediated; apoptosis ... See more keywords
Jietacin Derivative Inhibits TNF-α-Mediated Inflammatory Cytokines Production via Suppression of the NF-κB Pathway in Synovial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph16010005
Abstract: Synovial inflammation plays a central role in joint destruction and pain in osteoarthritis (OA). The NF-κB pathway plays an important role in the inflammatory process and is activated in OA. A previous study reported that… read more here.
Keywords: jietacin derivative; inflammatory cytokines; production; tnf mediated ... See more keywords
Electroacupuncture serum inhibits TNF-α-mediated chondrocyte inflammation via the Ras-Raf-MEK1/2-ERK1/2 signaling pathway
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2017.7366
Abstract: The Ras-Raf-mitogen-activated protein kinase kinase (MEK)1/2-extracellular signal-regulated kinase (ERK)1/2 signaling pathway contributes to the release of chondral matrix-degrading enzymes and accelerates the degradation of articular cartilage. Electroacupuncture (EA) treatment has been widely used for the… read more here.
Keywords: treatment; group; tnf mediated; signaling pathway ... See more keywords
Knockdown of the long non‑coding RNA MALAT1 ameliorates TNF‑α‑mediated endothelial cell pyroptosis via the miR‑30c‑5p/Cx43 axis
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2023.12977
Abstract: Long noncoding RNAs (lncRNAs) are related to the development of atherosclerosis (AS). However, the role of lncRNA metastasis associated lung adenocarcinoma transcript 1 (MALAT1) in tumor necrosis factor-α (TNF-α)-induced rat aortic endothelial cell (RAOEC) pyroptosis,… read more here.
Keywords: cell; cx43; pyroptosis; mir 30c ... See more keywords