Cannabinoid Receptor-2 Ameliorates Inflammation in Murine Model of Crohn’s Disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjx096
Abstract: Background and Aims Cannabinoid receptor stimulation may have positive symptomatic effects on inflammatory bowel disease [IBD] patients through analgesic and anti-inflammatory effects. The cannabinoid 2 receptor [CB2R] is expressed primarily on immune cells, including CD4+… read more here.
Keywords: disease; tnf mice; cannabinoid receptor; model ... See more keywords
TNFα Plays Essential Role in Resolution of Anemia of Inflammation in Tnfαko Mice Treated with Heat-Killed Brucella Abortus
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DOI: 10.1182/blood-2024-212272
Abstract: Anemia of inflammation (AI) is the second most prevalent form of anemia, and is common in patients with chronic inflammatory states, such as infection, autoimmunity, and cancer. There are no targeted treatments available for AI,… read more here.
Keywords: mice; tnf; role; inflammation ... See more keywords
Notoginsenoside R1 (NG-R1) Promoted Lymphatic Drainage Function to Ameliorating Rheumatoid Arthritis in TNF-Tg Mice by Suppressing NF-κB Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.730579
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disease that is primarily characterized by synovial inflammation. Our previous studies demonstrated that the lymphatic system is critical for the development and maintenance of RA disease, and sufficient… read more here.
Keywords: drainage; function; lymphatic drainage; rheumatoid arthritis ... See more keywords