Plasma let-7i, miR-16, and miR-221 levels as candidate biomarkers for the assessment of ankylosing spondylitis in Mexican patients naïve to anti-TNF therapy
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Rheumatology"
DOI: 10.1007/s10067-019-04509-1
Abstract: Novel biomarkers are needed for the diagnosis and clinical assessment of ankylosing spondylitis (AS). Our objective was to investigate plasma microRNAs differentially expressed between AS patients and controls and to evaluate their potential as biomarkers… read more here.
Keywords: tnf therapy; mir mir; mir 221; anti tnf ... See more keywords
Risk of Infections with Anti-TNF Agents in Patients with Crohn’s Disease After Elective Surgery
Sign Up to like & getrecommendations! Published in 2021 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-021-06976-6
Abstract: We read with interest the article by Hanzel et al. [1] conducting a systematic review and meta-analysis to investigate the relationship between preoperative biological therapy and postoperative outcomes in inflammatory bowel disease (IBD) focusing on… read more here.
Keywords: surgery; tnf therapy; anti tnf; postoperative complications ... See more keywords
Children with Localized Crohn's Disease Benefit from Early Ileocecal Resection and Perioperative Anti-Tumor Necrosis Factor Therapy
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DOI: 10.1055/s-0043-1764320
Abstract: Abstract Introduction In pediatric Crohn's disease ileocecal resection is performed reluctantly as postoperative recurrence is frequent. Anti-tumor necrosis factor (TNF) therapy reduces postoperative recurrence rates but increases the risk for infections. Materials and Methods We… read more here.
Keywords: tnf therapy; disease; crohn disease; therapy ... See more keywords
Antitumour necrosis factor alpha treatment in Crohn’s disease: long-term efficacy, side effects and need for surgery
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DOI: 10.1080/00365521.2022.2042592
Abstract: Abstract Objectives To examine the long-term efficacy and side effects of antitumour necrosis factor alpha (anti-TNF) therapy in patients with Crohn’s disease (CD), the need for surgery and the clinical outcome after discontinuing anti-TNF therapy.… read more here.
Keywords: side effects; anti tnf; therapy; tnf therapy ... See more keywords
Preoperative Anti-TNF Therapy is Associated with a Shorter Length of Resected Bowel in Patients Undergoing Ileocolic Resection for Crohn’s Disease
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DOI: 10.1080/08941939.2021.2023713
Abstract: Abstract Background Massive or repeated intestinal resections for Crohn’s disease (CD) could lead to disabling consequences. The present study aimed to assess the effect of preoperative anti-TNF therapy on the length of resected bowel and… read more here.
Keywords: anti tnf; tnf therapy; tnf; length resected ... See more keywords
Significant sE-Selectin levels reduction after 6 months of anti-TNF-α therapy in non-diabetic patients with moderate-to-severe psoriasis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Dermatological Treatment"
DOI: 10.1080/09546634.2017.1329498
Abstract: Abstract Purpose: Psoriasis patients have high risk of atherosclerosis, characterized by endothelial dysfunction. We aimed to study the association of the endothelial activation biomarkers monocyte chemoattractant protein 1 (MCP-1), soluble (s) E-selectin and P-selectin with… read more here.
Keywords: tnf therapy; patients moderate; anti tnf; psoriasis ... See more keywords
Anti TNF-α therapy for ulcerative colitis: current status and prospects for the future
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DOI: 10.1080/1744666x.2017.1243468
Abstract: ABSTRACT Introduction: Anti TNF-α agents have become a significant advance in the management of ulcerative colitis, proving to induce, with rapid onset, clinical and endoscopic remission. However, there is still a considerable unmet medical need… read more here.
Keywords: anti tnf; ulcerative colitis; tnf therapy; therapy ulcerative ... See more keywords
Tuberculosis Disease in Children and Adolescents on Therapy With Antitumor Necrosis Factor-ɑ Agents: A Collaborative, Multicenter Paediatric Tuberculosis Network European Trials Group (ptbnet) Study
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DOI: 10.1093/cid/ciz1138
Abstract: BACKGROUND: In adults, anti-tumor necrosis factor-α (TNF-α) therapy is associated with progression of latent tuberculosis (TB) infection (LTBI) to TB disease, but pediatric data are limited. METHODS: Retrospective multicenter study within the Paediatric Tuberculosis Network… read more here.
Keywords: necrosis factor; paediatric tuberculosis; tuberculosis; tnf therapy ... See more keywords
The Risk of Serious Infections Before and After Anti-TNF Therapy in Inflammatory Bowel Disease: A Retrospective Cohort Study
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DOI: 10.1093/ibd/izac097
Abstract: Abstract Background Serious infections have been observed in patients with inflammatory bowel disease (IBD) on anti-TNF use—but to what extent these infections are due to anti-TNF or the disease activity per se is hard to… read more here.
Keywords: anti tnf; tnf therapy; disease; inflammatory bowel ... See more keywords
Examination Under Anesthesia May Not Be Universally Required Prior to Anti-TNF Therapy in Perianal Crohn's Disease: A Comparative Cohort Study.
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DOI: 10.1093/ibd/izac143
Abstract: BACKGROUND Multidisciplinary care involving exam under anesthesia (EUA) and tumor necrosis factor (TNF) inhibitors is recommended for perianal Crohn's disease. However, the impact of this combined approach is not well established. METHODS We performed a… read more here.
Keywords: anti tnf; tnf therapy; perianal crohn; tnf ... See more keywords
Novel mRNA Signature for Anti-TNF-α Therapy Primary Response in Patients With Ulcerative Colitis.
Sign Up to like & getrecommendations! Published in 2023 at "Inflammatory bowel diseases"
DOI: 10.1093/ibd/izad060
Abstract: BACKGROUND Ulcerative colitis (UC), an idiopathic, chronic inflammatory disorder of the colonic mucosa, is commonly treated with antitumor necrosis factor α (anti-TNF-α) agents. However, only approximately two-thirds have an initial response to these therapies. METHODS… read more here.
Keywords: anti tnf; response; logor score; tnf therapy ... See more keywords