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   Articles with "tnfa" as a keyword



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Single nucleotide polymorphisms located in TNFA, IL1RN, IL6R, and IL6 genes are associated with COVID‐19 risk and severity in an Iranian population

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recommendations! Published in 2022 at "Cell Biology International"

DOI: 10.1002/cbin.11807

Abstract: Cytokines play pivotal functions in coronavirus disease 2019 (COVID‐19) pathogenesis. However, little is known about the rationale and importance of genetic variations associated with immune system responses, so‐called “immunogenetic profiling.” We studied whether polymorphisms of… read more here.

Keywords: tnfa il1rn; covid; tnfa; risk ... See more keywords
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Identification of TNFA influencing MDD risk and clinical features in Han Chinese.

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recommendations! Published in 2020 at "Cytokine"

DOI: 10.1016/j.cyto.2020.155030

Abstract: OBJECTIVE Our recent genetic-neuroimaging study observed that the rs1799724 polymorphism within the TNFA gene encoding TNF-α selectively affects the anatomy of visual cortex in patients with MDD. In this study, we hypothesized that TNFA is… read more here.

Keywords: tnfa; clinical features; mdd; rs1799724 polymorphism ... See more keywords

The Synergistic Effect of TNFA and IL10 Promoter Polymorphisms on Genetic Predisposition to Systemic Lupus Erythematosus.

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recommendations! Published in 2018 at "Genetic testing and molecular biomarkers"

DOI: 10.1089/gtmb.2017.0169

Abstract: AIMS We investigated the individual and combined effect of functional TNFA -308G/A and IL10 -1082G/A single nucleotide polymorphisms (SNPs) and their genotypes on the susceptibility to systemic lupus erythematosus (SLE) in a Bulgarian population. MATERIALS… read more here.

Keywords: tnfa; il10; systemic lupus; lupus erythematosus ... See more keywords
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TNFa regulates mitochondrial biogenesis via CREB phosphorylation in human airway smooth muscle

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recommendations! Published in 2023 at "Physiology"

DOI: 10.1152/physiol.2023.38.s1.5732514

Abstract: Airway inflammation is the central driver behind the pathogenesis of respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis, and the very recent pandemic outbreak of COVID-19. Previous studies reported that proinflammatory… read more here.

Keywords: increased mitochondrial; mitochondrial biogenesis; tnfa; physiology ... See more keywords