SAT0449 Sex, metabolic co-morbidities and line of therapy predict tnf-inhibitor therapy persistence in psoriatic arthritis: a retrospective cohort study
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DOI: 10.1136/annrheumdis-2017-eular.5178
Abstract: Background Although tumour necrosis factor-alpha inhibitor (TNFi) therapy has proven efficacy in the management of psoriatic arthritis (PsA), relatively little is known about predictors of TNFi persistence. Such knowledge would assist the application of stratified… read more here.
Keywords: tnfi; tnfi persistence; line; persistence ... See more keywords
FRI0626 Screening for tuberculosis before tnf inhibitor therapy remains suboptimal: a multi-specialty, real world, nationwide experience in the united states
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DOI: 10.1136/annrheumdis-2018-eular.5507
Abstract: Background: Tumor necrosis factor-a inhibitors (TNFi’s) effectively treat various autoimmune conditions, but drastically increase the risk of tuberculosis (TB) reactivation. Multiple international guidelines recommend screening for TB prior to initiating TNFi therapy. In the United… read more here.
Keywords: real world; inhibitor therapy; initiating tnfi; united states ... See more keywords
AB0301 ANTIMICROBIAL USE IS HIGH IN PATIENTS WITH INFLAMMATORY ARTHRITIDES, AND FURTHER INCREASES WITH FIRST-LINE TNFI THERAPY – NATIONWIDE RESULTS
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DOI: 10.1136/annrheumdis-2019-eular.6141
Abstract: Background Infections are well-known adverse effects of tumor necrosis factor inhibitors (TNFi) and increased hospitalization rates due to infections have also been reported. To our knowledge, this is the first study to report the effect… read more here.
Keywords: none declared; use; patients inflammatory; antimicrobial use ... See more keywords
IL-10 Induced by mTNF Crosslinking-Mediated Reverse Signaling in a Whole Blood Assay Is Predictive of Response to TNFi Therapy in Rheumatoid Arthritis
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DOI: 10.3390/jpm12061003
Abstract: (1) Background: To date, the response of patients with rheumatoid arthritis (RA) to the various biologic DMARD available cannot be predicted due to a lack of reliable biomarkers. Based on our preliminary work on tmTNF… read more here.
Keywords: therapy; tnfi therapy; blood assay; whole blood ... See more keywords