Antibody-Targeted TNFRSF Activation for Cancer Immunotherapy: The Role of FcγRIIB Cross-Linking
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DOI: 10.3389/fphar.2022.924197
Abstract: Co-stimulation signaling in various types of immune cells modulates immune responses in physiology and disease. Tumor necrosis factor receptor superfamily (TNFRSF) members such as CD40, OX40 and CD137/4-1BB are expressed on myeloid cells and/or lymphocytes,… read more here.
Keywords: cross linking; tnfrsf agonistic; agonistic antibodies; riib ... See more keywords