TNFSF15 is likely a susceptibility gene for systemic lupus erythematosus.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.05.098
Abstract: We aim to explore the correlation of TNFSF15 genetic polymorphisms with susceptibility to systemic lupus erythematosus (SLE). This study enrolled SLE patients and healthy individuals to detect three single nucleotide polymorphisms (SNPs) of TNFSF15 (rs3810936,… read more here.
Keywords: risk; susceptibility; sle; systemic lupus ... See more keywords
TNFSF15 Polymorphisms are Associated with Graves’ Disease and Graves’ Ophthalmopathy in a Han Chinese Population
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DOI: 10.1080/02713683.2019.1705494
Abstract: ABSTRACT Purpose Previous studies revealed an association of tumor necrosis factor super family-15 (TNFSF15) gene polymorphisms with several autoimmune diseases, but their roles in the development of Graves’ disease (GD) and Graves’ ophthalmopathy (GO) remain… read more here.
Keywords: tnfsf15; han chinese; chinese population; rs4979462 ... See more keywords
Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease
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DOI: 10.1371/journal.pgen.1007458
Abstract: Chronic inflammation in inflammatory bowel disease (IBD) results from a breakdown of intestinal immune homeostasis and compromise of the intestinal barrier. Genome-wide association studies have identified over 200 genetic loci associated with risk for IBD,… read more here.
Keywords: bowel disease; inflammatory bowel; expression; tnfsf15 ... See more keywords