Abstract 3452: TNG908, a brain-penetrant MTA-cooperative PRMT5 inhibitor, is efficacious in preclinical glioblastoma models
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DOI: 10.1158/1538-7445.am2023-3452
Abstract: Glioblastoma multiforme (GBM) is one of the most aggressive primary malignant brain tumors in adults. The median overall survival (OS) of GBM patients is poor (1-2 years) on standard of care therapies, which include surgery,… read more here.
Keywords: prmt5 inhibitor; tng908; brain; mta cooperative ... See more keywords