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   Articles with "tnni3k" as a keyword



Knockout of cardiac troponin I‐interacting kinase leads to cardiac dysfunction and remodelling

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recommendations! Published in 2022 at "Clinical and Experimental Pharmacology and Physiology"

DOI: 10.1111/1440-1681.13699

Abstract: Cardiac troponin I‐interacting kinase (TNNI3K) is a cardiac‐specific kinase that has been identified as a diagnostic marker and a therapeutic target in cardiovascular diseases. However, the biological function of TNNI3K in cardiac dysfunction and remodelling… read more here.

Keywords: tnni3k; kinase; troponin interacting; cardiac dysfunction ... See more keywords

Overexpression of Cardiac-Specific Kinase TNNI3K Promotes Mouse Embryonic Stem Cells Differentiation into Cardiomyocytes

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recommendations! Published in 2017 at "Cellular Physiology and Biochemistry"

DOI: 10.1159/000456400

Abstract: Backgroud/Aims: The biological function of cardiac troponin I-interacting kinase (TNNI3K), a cardiac-specific functional kinase, is largely unknown. We investigated the effect of human TNNI3K (hTNNI3K) on the differentiation of mouse embryonic stem cells (mESCs) into… read more here.

Keywords: kinase tnni3k; tnni3k; cardiac specific; overexpression ... See more keywords

Abstract Mo077: Cardiac Troponin I3 Kinase in Viral Myocarditis

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recommendations! Published in 2024 at "Circulation Research"

DOI: 10.1161/res.135.suppl_1.mo077

Abstract: Myocarditis is a leading cause of heart failure and sudden cardiac death. Often caused by viral infection, myocarditis is defined histopathologically as mononuclear immune infiltration in the heart muscle. While most patients recover with no… read more here.

Keywords: abstract mo077; heart; tnni3k; kinase ... See more keywords

Tnni3k alleles influence ventricular mononuclear diploid cardiomyocyte frequency

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recommendations! Published in 2019 at "PLoS Genetics"

DOI: 10.1371/journal.pgen.1008354

Abstract: Recent evidence implicates mononuclear diploid cardiomyocytes as a proliferative and regenerative subpopulation of the postnatal heart. The number of these cardiomyocytes is a complex trait showing substantial natural variation among inbred mouse strains based on… read more here.

Keywords: kinase; tnni3k; diploid cardiomyocyte; mononuclear diploid ... See more keywords

Whole-Exome Sequencing Identifies a Novel Variant (c.1538T > C) of TNNI3K in Arrhythmogenic Right Ventricular Cardiomyopathy

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recommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"

DOI: 10.3389/fcvm.2022.843837

Abstract: Backgrounds Arrhythmic right ventricular cardiomyopathy (ARVC) is a cardiomyopathy with a genetic predisposition that can lead to a sudden cardiac death and heart failure. According to the 2010 Task Force Criteria, genetic diagnosis is one… read more here.

Keywords: tnni3k; ventricular cardiomyopathy; whole exome; right ventricular ... See more keywords