A positive feedback loop between TNS1 and ZEB1 promotes TGFβ-induced epithelial-to-mesenchymal transition in lung cancer
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DOI: 10.1038/s42003-025-09079-4
Abstract: Epithelial-mesenchymal transition (EMT) plays a pivotal role in tumor metastasis initiation. Although emerging evidence suggests that Tensin-1 (TNS1) contributes to tumor metastasis, its precise function in EMT during lung cancer progression and the underlying mechanisms… read more here.
Keywords: lung cancer; tns1; tgf induced; zeb1 ... See more keywords
TNS1: Emerging Insights into Its Domain Function, Biological Roles, and Tumors
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DOI: 10.3390/biology11111571
Abstract: Simple Summary Tensin1 is a member of the tensin family, and tensins are adherent spot components. We summarize the role of tensin1 in various biological processes, such as cell adhesion, polarization, migration, invasion, proliferation, apoptosis,… read more here.
Keywords: biological processes; tns1; role; emerging insights ... See more keywords