Analysis of Gene Essentiality from TnSeq Data Using Transit.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1720-5_22
Abstract: TnSeq, or sequencing of transposon insertion libraries, has proven to be a valuable method for probing the functions of genes in a wide range of bacteria. TnSeq has found many applications for studying genes involved… read more here.
Keywords: analysis gene; transit; tnseq data; tnseq ... See more keywords
Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression
Sign Up to like & getrecommendations! Published in 2019 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-3156-z
Abstract: BackgroundDeep sequencing of transposon mutant libraries (or TnSeq) is a powerful method for probing essentiality of genomic loci under different environmental conditions. Various analytical methods have been described for identifying conditionally essential genes whose tolerance… read more here.
Keywords: regression; variability; zero inflated; inflated negative ... See more keywords