The Role of Rho-GTPases and actin polymerization during Macrophage Tunneling Nanotube Biogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-08950-7
Abstract: Macrophage interactions with other cells, either locally or at distances, are imperative in both normal and pathological conditions. While soluble means of communication can transmit signals between different cells, it does not account for all… read more here.
Keywords: tnt formation; biogenesis; macrophage; actin polymerization ... See more keywords
Intercellular mitochondrial transfer alleviates pyroptosis in dental pulp damage.
Sign Up to like & getrecommendations! Published in 2023 at "Cell proliferation"
DOI: 10.1111/cpr.13442
Abstract: Mitochondrial transfer is emerging as a promising therapeutic strategy for tissue repair, but whether it protects against pulpitis remains unclear. Here, we show that hyperactivated nucleotide-binding domain and leucine-rich repeat protein3 (NLRP3) inflammasomes with pyroptotic cell… read more here.
Keywords: tnt formation; transfer; dental pulp; bmscs ... See more keywords
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking
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DOI: 10.15252/embr.202052006
Abstract: Abstract Tunneling nanotubes (TNTs) are actin‐rich structures that connect two or more cells and mediate cargo exchange between spatially separated cells. TNTs transport signaling molecules, vesicles, organelles, and even pathogens. However, the molecular mechanisms regulating… read more here.
Keywords: tunneling nanotubes; mitochondrial trafficking; modulates mitochondrial; mical2pv ... See more keywords
Tunneling nanotube (TNT) formation is downregulated by cytarabine and NF-κB inhibition in acute myeloid leukemia (AML)
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DOI: 10.18632/oncotarget.13853
Abstract: Acute myeloid leukemia (AML) is a bone marrow derived blood cancer where intercellular communication in the leukemic bone marrow participates in disease development, progression and chemoresistance. Tunneling nanotubes (TNTs) are intercellular communication structures involved in… read more here.
Keywords: myeloid leukemia; leukemia aml; formation; tnt formation ... See more keywords