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Published in 2020 at "Clinical Microbiology and Infection"
DOI: 10.1016/j.cmi.2020.10.036
Abstract: Background Cytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated with multi-organ damage and death in severe COVID-19 disease. Objectives To perform a living systematic review of the literature about the efficacy and toxicity…
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Keywords:
covid patients;
risk;
review;
tocilizumab ... See more keywords
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Published in 2021 at "Journal of Internal Medicine"
DOI: 10.1111/joim.13231
Abstract: Published reports on tocilizumab in COVID‐19 pneumonitis show conflicting results due to weak designs or heterogeneity in critical methodological issues.
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Keywords:
medicine;
covid interstitial;
tocilizumab;
interstitial pneumonia ... See more keywords
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Published in 2020 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-020-05701-4
Abstract: Background Due to the lack of proven therapies, we evaluated the effects of early administration of tocilizumab for COVID-19. By inhibition of the IL-6 receptor, tocilizumab may help to mitigate the hyperinflammatory response associated with…
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Keywords:
covid patients;
patients cohort;
effects tocilizumab;
study ... See more keywords