Tocotrienol‐rich fraction attenuates UV‐induced inflammaging: A bench to bedside study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.12421
Abstract: UV radiation from the sun is the most common environmental stressor to damage the skin. It is now well established that photodamaged skin manifests signs of mild but chronic inflammation, termed as “inflammaging.” Thus, there… read more here.
Keywords: inflammaging bench; fraction attenuates; attenuates induced; rich fraction ... See more keywords
Tocotrienol-Rich Fraction Ameliorates Antioxidant Defense Mechanisms and Improves Replicative Senescence-Associated Oxidative Stress in Human Myoblasts
Sign Up to like & getrecommendations! Published in 2017 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2017/3868305
Abstract: During aging, oxidative stress affects the normal function of satellite cells, with consequent regeneration defects that lead to sarcopenia. This study aimed to evaluate tocotrienol-rich fraction (TRF) modulation in reestablishing the oxidative status of myoblasts… read more here.
Keywords: replicative senescence; oxidative stress; senescence; rich fraction ... See more keywords
TOCOTRIENOL-RICH FRACTION MODULATE THE PHOSPHOINOSITIDE 3-KINASES/AKT SIGNALING PATHWAY GENES AND PREVENT OXIDATIVE STRESS IN NICOTINE-INDUCED PRE-IMPLANTATION EMBRYOS
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2019.v11s5.t0055
Abstract: Objective: This study aimed to determine the effects of the tocotrienol-rich fraction (TRF) on the regulations of phosphoinositide 3-kinases (PI3K)/Aktpathways related genes in preimplantation embryos induced by nicotine (Nic).Methods: Twenty-four female BALB/c mice were divided… read more here.
Keywords: akt signaling; phosphoinositide kinases; signaling pathway; rich fraction ... See more keywords
Comparing Palm Oil, Tocotrienol-Rich Fraction and α-Tocopherol Supplementation on the Antioxidant Levels of Older Adults
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DOI: 10.3390/antiox7060074
Abstract: Background: Tocotrienol and tocopherol are known to prevent numerous degenerative diseases. The aim of this study is to compare the effects of tocotrienol-rich fraction (TRF) with α-tocopherol (α-TF) on the antioxidant status of healthy individuals… read more here.
Keywords: supplementation; six months; rich fraction; tocopherol ... See more keywords
The Modulation of NMDA and AMPA/Kainate Receptors by Tocotrienol-Rich Fraction and Α-Tocopherol in Glutamate-Induced Injury of Primary Astrocytes
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DOI: 10.3390/biomedicines5040068
Abstract: Astrocytes are known as structural and supporting cells in the central nervous system (CNS). Glutamate, as a main excitatory amino acid neurotransmitter in the mammalian central nervous system, can be excitotoxic, playing a key role… read more here.
Keywords: primary astrocytes; glutamate; rich fraction; tocopherol ... See more keywords
The Effects of Tocotrienol-Rich Vitamin E (Tocovid) on Diabetic Neuropathy: A Phase II Randomized Controlled Trial
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DOI: 10.3390/nu12051522
Abstract: Chronic hyperglycemia increases oxidative stress, activates inflammatory pathways and reduces nerve growth factor (NGF) among diabetic patients, which contribute to development of diabetic peripheral neuropathy (DPN). Tocotrienol-Rich Vitamin E (Tocovid) possesses potent antioxidant and anti-inflammatory… read more here.
Keywords: nerve conduction; tocovid; rich vitamin; tocotrienol rich ... See more keywords
Tocotrienol-Rich Fraction and Levodopa Regulate Proteins Involved in Parkinson’s Disease-Associated Pathways in Differentiated Neuroblastoma Cells: Insights from Quantitative Proteomic Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14214632
Abstract: Tocotrienol-rich fraction (TRF), a palm oil-derived vitamin E fraction, is reported to possess potent neuroprotective effects. However, the modulation of proteomes in differentiated human neuroblastoma SH-SY5Y cells (diff-neural cells) by TRF has not yet been… read more here.
Keywords: tocotrienol rich; rich fraction; analysis; neural cells ... See more keywords
Tocotrienol-Rich Fraction Ameliorates the Aluminium Chloride-Induced Neurovascular Dysfunction-Associated Vascular Dementia in Rats
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DOI: 10.3390/ph16060828
Abstract: Neurovascular dysfunction leads to the second most common type of dementia, i.e., vascular dementia (VaD). Toxic metals, such as aluminium, increase the risk of neurovascular dysfunction-associated VaD. Hence, we hypothesized that a natural antioxidant derived… read more here.
Keywords: tocotrienol rich; neurovascular dysfunction; dysfunction associated; dysfunction ... See more keywords
Comparing the effects of vitamin E tocotrienol-rich fraction supplementation and α-tocopherol supplementation on gene expression in healthy older adults
Sign Up to like & getrecommendations! Published in 2019 at "Clinics"
DOI: 10.6061/clinics/2019/e688
Abstract: OBJECTIVES This study aims to compare the differential gene expression resulting from tocotrienol-rich fraction and α-tocopherol supplementation in healthy older adults. METHODS A total of 71 eligible subjects aged 50 to 55 years from Gombak… read more here.
Keywords: supplementation; expression; rich fraction; tocopherol ... See more keywords