Homogeneous and Universal Detection of Various Targets with a Dual‐Step Transduced Toehold Switch Sensor
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DOI: 10.1002/cbic.201900749
Abstract: Toehold switch sensors represent a class of new advances that allow specific targets to trigger in situ expression of a protein reporter. Although they offer unique advantages of a label‐free nature and high portability, they… read more here.
Keywords: dual step; toehold switch; switch; switch sensor ... See more keywords
Development of a Cell-Free, Toehold Switch-Based Biosensor for Rapid and Sensitive Zika Virus Detection.
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DOI: 10.1021/acs.analchem.4c05808
Abstract: The need for rapid and sensitive diagnostic tools is emphasized by the significant impact of infectious diseases on global health. This study presents a cell-free biosensor utilizing toehold switch technology, combined with nucleic acid sequence-based… read more here.
Keywords: detection; cell free; toehold switch; zika virus ... See more keywords
Transcriptional Interference in Toehold Switch-Based RNA Circuits.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00486
Abstract: Gene regulation based on regulatory RNA is an important mechanism in cells and is increasingly used for regulatory circuits in synthetic biology. Toehold switches are rationally designed post-transcriptional riboregulators placed in the 5' untranslated region… read more here.
Keywords: promoter; rna; toehold switch; transcriptional interference ... See more keywords