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Published in 2020 at "OncoTargets and therapy"
DOI: 10.2147/ott.s273866
Abstract: Background Post hoc analysis of the LUX-Lung 3 and 6 (LL3/6) Phase III trials showed that tolerability-guided dose-adjustments of afatinib reduced treatment-related adverse events (TRAEs) without affecting progression-free survival (PFS) in patients with epidermal growth…
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Keywords:
lux lung;
dose reduction;
dose adjustments;
tolerability guided ... See more keywords