Ways Forward for Tolerance-Inducing Cellular Therapies- an AFACTT Perspective
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DOI: 10.3389/fimmu.2019.00181
Abstract: Clinical studies with cellular therapies using tolerance-inducing cells, such as tolerogenic antigen-presenting cells (tolAPC) and regulatory T cells (Treg) for the prevention of transplant rejection and the treatment of autoimmune diseases have been expanding the… read more here.
Keywords: forward tolerance; inducing cellular; tolerance inducing; cellular therapies ... See more keywords
Mechanistic and Biomarker Studies to Demonstrate Immune Tolerance in Multiple Sclerosis
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DOI: 10.3389/fimmu.2021.787498
Abstract: The induction of specific immunological tolerance represents an important therapeutic goal for multiple sclerosis and other autoimmune diseases. Sound knowledge of the target antigens, the underlying pathomechanisms of the disease and the presumed mechanisms of… read more here.
Keywords: mechanistic biomarker; immune tolerance; tolerance inducing; tolerance ... See more keywords