Tolerance After Liver Transplantation: Where Are We?
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DOI: 10.1002/lt.25294
Abstract: We have read with great interest the review article by Feng and Bucuvalas1 . They revised from a molecular to a clinical point of view all aspects regarding immune tolerance(IT) after liver transplantation(LT), including all… read more here.
Keywords: tolerance liver; transplantation; liver transplantation; transplantation tolerance ... See more keywords
Extracellular adenosine reversibly inhibits the activation of human regulatory T cells and negatively influences the achievement of the operational tolerance in liver transplantation
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DOI: 10.1111/ajt.15023
Abstract: The artificial induction of tolerance in transplantation is gaining strength. In mice, a differential role of extracellular adenosine (eADO) for regulatory and effector T cells (Tregs and Teffs, respectively) has been proposed: inhibiting Teffs and… read more here.
Keywords: extracellular adenosine; tolerance; tolerance liver; transplantation ... See more keywords
Strategies for Deliberate Induction of Immune Tolerance in Liver Transplantation: From Preclinical Models to Clinical Application
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DOI: 10.3389/fimmu.2020.01615
Abstract: The liver exhibits intrinsic immune regulatory properties that maintain tolerance to endogenous and exogenous antigens, and provide protection against pathogens. Such an immune privilege contributes to susceptibility to spontaneous acceptance despite major histocompatibility complex mismatch… read more here.
Keywords: strategies deliberate; tolerance; tolerance liver; immune tolerance ... See more keywords