Tolerance and Pharmacokinetics of Galliprant™ Administered Orally to Collies Homozygous for MDR1-1Δ.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of veterinary pharmacology and therapeutics"
DOI: 10.1111/jvp.12984
Abstract: The objectives of the study were to evaluate the pharmacokinetics and tolerance of grapiprant, a substrate of the human P-gp transporter, in collies homozygous for MDR1-1Δ when administered at the labeled dosage of 2 mg/kg once… read more here.
Keywords: tolerance pharmacokinetics; collies homozygous; homozygous mdr1; pharmacokinetics galliprant ... See more keywords
Safety, dose tolerance, pharmacokinetics, and pharmacodynamics of fosciclopirox (CPX-POM) in patients with advanced solid tumors.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.6_suppl.518
Abstract: 518Background: Fosciclopirox (CPX-POM) is being developed for the treatment of non-muscle invasive and muscle invasive bladder cancer. CPX-POM selectively delivers its active metabolite, ciclopirox... read more here.
Keywords: cpx pom; fosciclopirox cpx; tolerance pharmacokinetics; safety dose ... See more keywords