Oral Glucose Tolerance Test: An Informative Endpoint or an Added Burden in Metformin Drug–Drug Interaction Studies?
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2650
Abstract: For drugs that inhibit organic cation transporters and/or multidrug and toxin extrusion proteins, a metformin clinical drug– drug interaction (DDI) study is recommended to assess the impact on metformin’s systemic exposure. An oral glucose tolerance… read more here.
Keywords: tolerance test; glucose tolerance; drug drug; oral glucose ... See more keywords
The utility of glucose area under the curve from the oral glucose tolerance test as a screening tool for cystic fibrosis‐related diabetes
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.26100
Abstract: Consistently abnormal glucose levels on oral glucose tolerance test (OGTT) are the most effective screening tool for cystic fibrosis‐related diabetes (CFRD). However, some cystic fibrosis (CF) patients demonstrate abnormal glucose profiles not reaching levels required… read more here.
Keywords: glucose tolerance; screening tool; oral glucose; tolerance test ... See more keywords
The monophasic pattern in oral glucose tolerance test as a predictive risk factor of type 2 diabetes in obese paediatric patients
Sign Up to like & getrecommendations! Published in 2017 at "Anales De Pediatria"
DOI: 10.1016/j.anpede.2017.08.003
Abstract: Abstract Introduction The onset of obesity at young ages is strongly associated with the early development of type 2 diabetes (T2D). The shape of the curves of glucose and insulin curves during an oral glucose… read more here.
Keywords: risk; monophasic pattern; type diabetes; tolerance test ... See more keywords
Hypoglycaemia on an oral glucose tolerance test in pregnancy - Is it clinically significant?
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2018.11.018
Abstract: AIM During pregnancy, some women have a low glucose level on the 75 g oral glucose tolerance test (OGTT). The implications of this are unclear and there is no guideline on how to manage these women.… read more here.
Keywords: pregnancy; group; tolerance test; glucose tolerance ... See more keywords
Diagnosis of disorders of glucose tolerance in women with polycystic ovary syndrome (PCOS) at a tertiary care center: fasting plasma glucose or oral glucose tolerance test?
Sign Up to like & getrecommendations! Published in 2019 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2019.01.015
Abstract: BACKGROUND The risk of developing prediabetes and type 2 diabetes (dysglycemia) may be increased in women with PCOS. Whether an oral glucose tolerance test (OGTT) should be performed routinely in all PCOS women at presentation… read more here.
Keywords: plasma glucose; tolerance test; glucose tolerance; women pcos ... See more keywords
Rethinking the accuracy of 75g glucose used in the oral glucose tolerance test in the diagnosis and management of diabetes.
Sign Up to like & getrecommendations! Published in 2017 at "Primary care diabetes"
DOI: 10.1016/j.pcd.2017.06.003
Abstract: AIMS We investigated the specificity of the 75g oral glucose tolerance test (OGTT) and the clinical usefulness of the 2h post loading glucose (2h PLG) value in the clinical care of diabetes patients. METHODS The… read more here.
Keywords: plg; tolerance test; management diabetes; glucose tolerance ... See more keywords
The response of C19- and some C21-steroids during Synacthen and insulin tolerance test
Sign Up to like & getrecommendations! Published in 2018 at "Steroids"
DOI: 10.1016/j.steroids.2018.01.009
Abstract: HighlightsThe response of steroid metabolites might be also a marker of adrenal activity.Various dose Synacthen tests implicate earlier or later maximal steroids response.Decrease of steroid conjugates by hypoglycaemia in first 20 min of the test.Conjugated… read more here.
Keywords: response; tolerance test; test; synacthen tests ... See more keywords
Effects of oral glucose tolerance test on microvascular and autonomic nervous system regulation in young healthy individuals
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-18209-1
Abstract: Acute elevations in blood glucose can influence microvascular function and autonomic nervous system (ANS) reactivity, both implicated in cardiometabolic risk. We assessed the effects of oral glucose tolerance test (OGTT) on microvascular and ANS physiological… read more here.
Keywords: nervous system; effects oral; glucose tolerance; oral glucose ... See more keywords
Diagnosis of lactose intolerance: concordance between 13910-C/T genotype and lactose tolerance test in a Danish population
Sign Up to like & getrecommendations! Published in 2024 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2024.2417273
Abstract: Abstract The association between the MCM6-13910-C/T polymorphism and lactose intolerance in individuals of European descent is well known. However, the notion that having a single versus a double allelic mutation might influence one’s phenotype has… read more here.
Keywords: tolerance test; genotype; lactose intolerance; test ... See more keywords
The Reproducibility of an Abbreviated Fat Tolerance Test in Young Healthy Participants: A Pilot Study (P12-029-19).
Sign Up to like & getrecommendations! Published in 2019 at "Current developments in nutrition"
DOI: 10.1093/cdn/nzz035.p12-029-19
Abstract: Objectives Triglyceride (TG) responses following a high-fat meal are more strongly associated with cardiovascular disease (CVD) risk compared with fasting TG levels. The current protocol for assessing post-meal TG is a burdensome process, involving serial… read more here.
Keywords: hour; tolerance test; reproducibility; aftt ... See more keywords
Outcome of Pregnancy Oral Glucose Tolerance Test and Preterm Birth
Sign Up to like & getrecommendations! Published in 2024 at "Epidemiology"
DOI: 10.1097/ede.0000000000001752
Abstract: Background: Gestational diabetes is associated with adverse outcomes such as preterm birth ( read more here.
Keywords: birth; glucose tolerance; oral glucose; gestational diabetes ... See more keywords