Removal of chromatin by salt-tolerant endonucleases for production of recombinant measles virus.
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology progress"
DOI: 10.1002/btpr.3342
Abstract: Host cell DNA is a critical impurity in downstream processing of enveloped viruses. Especially, DNA in the form of chromatin is often neglected. Endonuclease treatment is an almost mandatory step in manufacturing of viral vaccines.… read more here.
Keywords: tolerant endonucleases; measles virus; salt tolerant; recombinant measles ... See more keywords