Iron-Sensitive Prodrugs That Trigger Active Ferroptosis in Drug-Tolerant Pancreatic Cancer Cells.
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DOI: 10.1021/jacs.2c03973
Abstract: Persister cancer cells represent rare populations of cells resistant to therapy. Cancer cells can exploit epithelial-mesenchymal plasticity to adopt a drug-tolerant state that does not depend on genetic alterations. Small molecules that can interfere with… read more here.
Keywords: cancer; tolerant pancreatic; drug tolerant; cancer cells ... See more keywords