Tolerogenic Dendritic Cells in Autoimmunity and Inflammatory Diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in immunology"
DOI: 10.1016/j.it.2020.11.001
Abstract: Dendritic cells (DCs), the most efficient antigen-presenting cells, are necessary for the effective activation of naïve T cells. DCs can also acquire tolerogenic functions in vivo and in vitro in response to various stimuli, including… read more here.
Keywords: dcs; autoimmunity inflammatory; inflammatory diseases; dendritic cells ... See more keywords
Identification of 14-dehydroergosterol as a novel anti-inflammatory compound inducing tolerogenic dendritic cells
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-14446-1
Abstract: Tolerogenic dendritic cells (DCs) have the ability to induce regulatory T cells and play an important role in preventing chronic inflammatory and autoimmune diseases. We have identified a novel compound, 14-dehydroergosterol, from Koji, a Japanese… read more here.
Keywords: dcs; inflammatory; dendritic cells; compound ... See more keywords
Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota That Protects From Metabolic Diseases
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DOI: 10.2337/db20-1177
Abstract: Excess chronic contact between microbial motifs and intestinal immune cells is known to trigger a low-grade inflammation involved in many pathologies such as obesity and diabetes. The important skewing of intestinal adaptive immunity in the… read more here.
Keywords: microbiota; cells shape; dendritic cells; mice ... See more keywords
MAP7 and MUCL1 Are Biomarkers of Vitamin D3-Induced Tolerogenic Dendritic Cells in Multiple Sclerosis Patients
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.01251
Abstract: The administration of autologous tolerogenic dendritic cells (tolDC) has become a promising alternative for the treatment of autoimmune diseases, such as multiple sclerosis (MS). Specifically, the use of vitamin D3 for the generation of tolDC… read more here.
Keywords: vitd3 toldc; dendritic cells; map7 mucl1; multiple sclerosis ... See more keywords
Tolerogenic dendritic cells pulsed with islet antigen induce long-term reduction in T-cell autoreactivity in type 1 diabetes patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1054968
Abstract: Introduction Restoration of immune tolerance may halt progression of autoimmune diseases. Tolerogenic dendritic cells (tolDC) inhibit antigen-specific proinflammatory T-cells, generate antigen-specific regulatory T-cells and promote IL-10 production in-vitro, providing an appealing immunotherapy to intervene in… read more here.
Keywords: cell; tolerogenic dendritic; type diabetes; dendritic cells ... See more keywords