Muscarinic receptor binding of fesoterodine, 5-hydroxymethyl tolterodine, and tolterodine in rat tissues after the oral, intravenous, or intravesical administration.
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DOI: 10.1016/j.jphs.2019.05.001
Abstract: The present study aimed to characterize muscarinic receptor binding of fesoterodine, 5-hydroxymethyl tolterodine (5-HMT), and tolterodine in bladder and other tissues of rats after their oral, intravenous, or intravesical administration. Muscarinic receptors in tissues were… read more here.
Keywords: tolterodine; muscarinic receptors; muscarinic receptor; hmt ... See more keywords
In Vitro and In Vivo Metabolic Activation of Tolterodine Mediated by CYP3A.
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DOI: 10.1021/acs.chemrestox.2c00389
Abstract: Tolterodine (TOL) is an antimuscarinic drug used for the treatment of patients with overactive bladder presenting urinary frequency, urgency, and urge incontinence. During the clinical use of TOL, adverse events such as liver injury took… read more here.
Keywords: tolterodine; metabolic activation; gsh conjugate; tol ... See more keywords
Characteristics of antimuscarinic responders versus suboptimal responders in a randomized clinical trial of patients with overactive bladder symptoms
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DOI: 10.1080/03007995.2017.1361914
Abstract: Abstract Objective: To assess the characteristics of tolterodine extended-release (ER) 4 mg responders and suboptimal responders (≤50% decrease in UUI episodes/24 h) among patients with overactive bladder (OAB), including urgency urinary incontinence (UUI), and identify predictors of… read more here.
Keywords: tolterodine; week; uui episodes; suboptimal responders ... See more keywords
Comparisons of Therapeutic Efficacy and Safety of Solifenacin versus Tolterodine in Patients with Overactive Bladder: A Meta-Analysis
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DOI: 10.1159/000497311
Abstract: Objectives: This meta-analysis was to assess solifenacin and tolterodine in patients with overactive bladder. Methods: We searched PubMed, the Cochrane Library, EMBASE, CNKI, Wanfang, and ClinicalTrials.gov databases for randomized controlled trials (RCTs). The efficacy endpoint… read more here.
Keywords: tolterodine; solifenacin; micturition; tolterodine patients ... See more keywords
Association between different anticholinergic drugs and subsequent dementia risk in patients with diabetes mellitus
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DOI: 10.1371/journal.pone.0175335
Abstract: Background The effects of oxybutynin, solifenacin and tolterodine on dementia risk in patients with diabetes mellitus (DM) remain unknown. We investigated the effects of oxybutynin, solifenacin and tolterodine on dementia risk in patients with DM.… read more here.
Keywords: dementia risk; tolterodine; oxybutynin solifenacin; dementia ... See more keywords
Comparison of micro-radiofrequency therapy and tolterodine for the treatment of newly diagnosed overactive bladder: A retrospective cohort study
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DOI: 10.3389/fnins.2023.1120843
Abstract: Purpose This study aimed to retrospectively compare the efficacy and safety of micro-radiofrequency (RF) therapy through the urethra vs. oral tolterodine tartrate in the treatment of newly diagnosed overactive bladder (OAB). Materials and methods In… read more here.
Keywords: newly diagnosed; therapy; tolterodine; group ... See more keywords
Clinical efficacy and safety of tolterodine in the treatment of the children with bladder spasm after cystostomy
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DOI: 10.3760/cma.j.issn.1673-4416.2018.04.018
Abstract: Objective To evaluate the efficacy and safety of tolterodine in children with bladder spasm after cystostomy. Methods A total of 60 children between 5 and 12 years old operated by cystostomy were enrolled. Thirty-two children… read more here.
Keywords: tolterodine; safety; group; bladder spasm ... See more keywords