Minocycline prevents neuronal hyperexcitability and neuroinflammation in medial prefrontal cortex, as well as memory impairment caused by repeated toluene inhalation in adolescent rats.
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DOI: 10.1016/j.taap.2020.114980
Abstract: Toluene can be intentionally misused by adolescents to experience psychoactive effects. Toluene has a complex mechanism of action and broad behavioral effects, among which memory impairment is reported consistently. We have previously reported that repeated… read more here.
Keywords: hyperexcitability; toluene inhalation; memory impairment; repeated toluene ... See more keywords