Structural characterization and bioactivity profiling of the fungal peptaibiotic tolypin reveal protective effects against influenza viruses
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DOI: 10.1002/ardp.202400384
Abstract: In a bioprospection for new antivirals, we tested nonribosomally biosynthesized polypeptide antibiotics in MDCK II cells for their actions on influenza A and B viruses (IAV/IBV). Only tolypin, a mixture of closely related 16âresidue peptaibiotics… read more here.
Keywords: mdck cells; tolypin; characterization bioactivity; structural characterization ... See more keywords