Tomentosin Induces Telomere Shortening and Caspase‐Dependant Apoptosis in Cervical Cancer Cells
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DOI: 10.1002/jcb.25826
Abstract: Tomentosin, a natural sesquiterpene lactone purified from of Inula viscosa L., was investigated for its anti‐proliferative, telomere shortening, and apoptotic effects on human cervical cancer HeLa and SiHa cell lines. Tomentosin was found to inhibit… read more here.
Keywords: caspase; telomere shortening; apoptosis; cervical cancer ... See more keywords
Design, Synthesis, and Biological Evaluation of Novel Tomentosin Derivatives in NMDA-Induced Excitotoxicity
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DOI: 10.3390/ph15040421
Abstract: N-methyl-D-aspartate (NMDA) receptor stimulation may lead to excitotoxicity, which triggers neuronal death in brain disorders. In addition to current clinical therapeutic approaches, treatment strategies by phytochemicals or their derivatives are under investigation for neurodegenerative diseases.… read more here.
Keywords: tomentosin derivatives; nmda induced; novel; excitotoxicity ... See more keywords