TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis
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DOI: 10.1002/1878-0261.70002
Abstract: Chondrosarcomas are common bone sarcomas frequently resistant to radiation and chemotherapy, with high recurrence rates, development of metastatic disease, and death. Fibrosarcomas are soft tissue sarcomas associated with poor outcomes. Translocase of outer mitochondrial membrane… read more here.
Keywords: cancer; resistance; tomm20; cancer aggressiveness ... See more keywords
TOMM20 as a potential therapeutic target of colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "BMB Reports"
DOI: 10.5483/bmbrep.2019.52.12.249
Abstract: Translocase of outer mitochondrial membrane 20 (TOMM20) plays an essential role as a receptor for proteins targeted to mitochondria. TOMM20 was shown to be overexpressed in various cancers. However, the oncological function and therapeutic potential… read more here.
Keywords: therapeutic target; cancer; tomm20; target colorectal ... See more keywords