TonB-Dependent Utilization of Dihydroxamate Xenosiderophores in Synechocystis sp. PCC 6803
Sign Up to like & getrecommendations! Published in 2017 at "Current Microbiology"
DOI: 10.1007/s00284-017-1355-2
Abstract: In Gram-negative bacteria, transport of ferric siderophores through outer membrane is a complex process that requires specific outer membrane transporters and energy-transducing TonB–ExbB–ExbD system in the cytoplasmic membrane. The genome of the non-siderophore-producing cyanobacterium Synechocystis… read more here.
Keywords: tonb dependent; pcc 6803; synechocystis pcc; iron ... See more keywords
NMR assignments of the N-terminal signaling domain of the TonB-dependent outer membrane transducer PupB
Sign Up to like & getrecommendations! Published in 2018 at "Biomolecular NMR Assignments"
DOI: 10.1007/s12104-017-9785-0
Abstract: Outer membrane TonB-dependent transducers (TBDTs) actively transport ferric siderophore complexes from the extracellular environment into Gram-negative bacteria. They also participate in a cell-surface signaling regulatory pathway that results in upregulation of the transducer itself, in… read more here.
Keywords: tonb dependent; nmr assignments; outer membrane; terminal signaling ... See more keywords
A new collagenase enzyme of the marine sponge pathogen Pseudoalteromonas agarivorans NW4327 is uniquely linked with a TonB dependent receptor.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.11.106
Abstract: The primary pathogen of the Great Barrier Reef sponge Rhopaloeides odorabile, recently identified as a novel strain (NW4327) of Pseudoalteromonas agarivorans, produced collagenase which degraded R. odorabile skeletal fibers. We now report the collagenase of… read more here.
Keywords: tonb dependent; dependent receptor; sponge; collagenase ... See more keywords
TonB Dependent Receptors Affect the Spontaneous Oxytetracycline Resistance Evolution in Aeromonas hydrophila.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.9b00708
Abstract: It is well known that most microbial populations develop their intrinsic antibiotics resistance at low concentrations of antibiotics environments, but the influence factors of spontaneous resistance are still largely unknown. In this study, Aeromonas hydrophila… read more here.
Keywords: tonb dependent; evolution; resistance; resistance evolution ... See more keywords
Gating of TonB-dependent transporters by substrate-specific forced remodelling
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms14804
Abstract: Membrane proteins play vital roles in inside-out and outside-in signal transduction by responding to inputs that include mechanical stimuli. Mechanical gating may be mediated by the membrane or by protein(s) but evidence for the latter… read more here.
Keywords: dependent transporters; tonb dependent; specific forced; transporters substrate ... See more keywords
A TonB-dependent transporter is required for secretion of protease PopC across the bacterial outer membrane
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09366-9
Abstract: TonB-dependent transporters (TBDTs) are ubiquitous outer membrane β-barrel proteins that import nutrients and bacteriocins across the outer membrane in a proton motive force-dependent manner, by directly connecting to the ExbB/ExbD/TonB system in the inner membrane.… read more here.
Keywords: popc; tonb dependent; secretion; outer membrane ... See more keywords
A TonB-dependent receptor constitutes the outer membrane transport system for a lignin-derived aromatic compound
Sign Up to like & getrecommendations! Published in 2019 at "Communications Biology"
DOI: 10.1038/s42003-019-0676-z
Abstract: TonB-dependent receptors (TBDRs) mediate substrate-specific transport across the outer membrane, utilizing energy derived from the proton motive force transmitted from the TonB−ExbB−ExbD complex located in the inner membrane (TonB system). Although a number of TonB… read more here.
Keywords: lignin derived; tonb dependent; membrane transport; outer membrane ... See more keywords
Fluorescence High-Throughput Screening for Inhibitors of TonB Action
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Bacteriology"
DOI: 10.1128/jb.00889-16
Abstract: ABSTRACT Gram-negative bacteria acquire ferric siderophores through TonB-dependent outer membrane transporters (TBDT). By fluorescence spectroscopic hgh-throughput screening (FLHTS), we identified inhibitors of TonB-dependent ferric enterobactin (FeEnt) uptake through Escherichia coli FepA (EcoFepA). Among 165 inhibitors… read more here.
Keywords: tonb dependent; fluorescence; inhibitors tonb; gram negative ... See more keywords
Plant-Derived Catechols Are Substrates of TonB-Dependent Transporters and Sensitize Pseudomonas aeruginosa to Siderophore-Drug Conjugates
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.01498-22
Abstract: Iron is an essential element for living organisms. Most bacteria synthesize species-specific iron chelators, called siderophores, able to capture iron from their host or the environment. Pseudomonas aeruginosa, an opportunistic pathogen, produces two endogenous siderophores… read more here.
Keywords: pseudomonas aeruginosa; siderophore drug; iron; tonb dependent ... See more keywords
Mutation of TonB-Dependent Receptor Encoding Gene MCR_0492 Potentially Associates with Macrolides Resistance in Moraxella catarrhalis Isolates
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s364397
Abstract: Introduction Moraxella catarrhalis, which is an opportunistic pathogen and is one of the three major pathogens of community-acquired pneumonia, causes a variety of infections in clinic. In recent years, the isolation rate of Moraxella catarrhalis… read more here.
Keywords: moraxella; moraxella catarrhalis; resistance; tonb dependent ... See more keywords