Identification of novel subtypes based on ssGSEA in immune-related prognostic signature for tongue squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer medicine"
DOI: 10.1002/cam4.4341
Abstract: BACKGROUND Tongue squamous cell carcinoma (TSCC) is characterized by aggressive invasion and poor prognosis. Currently, immune checkpoint inhibitors may prolong overall survival compared with conventional treatments. However, PD1/PDL1 remain inapplicable in predicting the prognosis of TSCC;… read more here.
Keywords: tongue squamous; ssgsea; immune related; squamous cell ... See more keywords
Cyclin‐dependent kinase 5 promotes the growth of tongue squamous cell carcinoma through the microRNA 513c‐5p/cell division cycle 25B pathway and is associated with a poor prognosis
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34136
Abstract: The objective of this study was to investigate the role and molecular mechanism of cyclin‐dependent kinase 5 (CDK5) in regulating the growth of tongue squamous cell carcinoma (TSCC). read more here.
Keywords: cell; tongue squamous; dependent kinase; squamous cell ... See more keywords
Prognostic outcomes of treatment naïve oral tongue squamous cell carcinoma (OTSCC): a comprehensive analysis of 14 years
Sign Up to like & getrecommendations! Published in 2020 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-020-06482-x
Abstract: To analyze the factors predicting survival outcomes in treatment naïve oral tongue squamous cell carcinoma (OTSCC). A comprehensive review of 531 oral tongue carcinoma patients treated with upfront surgery followed by adjuvant radiotherapy or chemoradiotherapy… read more here.
Keywords: tongue squamous; carcinoma; oral tongue; treatment oral ... See more keywords
Oral tongue squamous cell carcinomas in young patients according to their smoking status: a GETTEC study
Sign Up to like & getrecommendations! Published in 2021 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-021-06793-7
Abstract: Incidence of oral tongue squamous cell carcinoma (OTSCC) is increasing, especially in young adults, despite decreasing tobacco and alcohol consumption. This multicentric retrospective study of 185 young adults with OTSCC (median follow-up 43 months), investigated… read more here.
Keywords: tongue squamous; oral tongue; young patients; squamous cell ... See more keywords
Usefulness of contrast-enhanced CT in the evaluation of depth of invasion in oral tongue squamous cell carcinoma: comparison with MRI
Sign Up to like & getrecommendations! Published in 2020 at "Oral Radiology"
DOI: 10.1007/s11282-020-00429-y
Abstract: Objectives There is currently no standardized approach for assessing the depth of invasion (DOI) of oral tongue squamous cell carcinoma via diagnostic imaging. We investigated the usefulness of contrast-enhanced computed tomography (CECT) for estimating the… read more here.
Keywords: tongue squamous; pathological doi; oral tongue; squamous cell ... See more keywords
Bafilomycin A1 increases the sensitivity of tongue squamous cell carcinoma cells to cisplatin by inhibiting the lysosomal uptake of platinum ions but not autophagy.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.03.003
Abstract: The role of autophagy in tongue squamous cell carcinoma (TSCC) cisplatin resistance is unclear. We aimed to identify a possible synergistic effect of autophagy inhibitors and cisplatin in TSCC cells and explore the underlying mechanism.… read more here.
Keywords: tongue squamous; platinum; bafilomycin; tscc ... See more keywords
CBX3 promotes tumor proliferation by regulating G1/S phase via p21 downregulation and associates with poor prognosis in tongue squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.02.043
Abstract: Chromobox protein homolog 3 (CBX3), a core component of the heterochromatin proteins 1, is recently proved to be involved in human cancerogenesis and associated with the prognosis of patient. However, the role of CBX3 in… read more here.
Keywords: tongue squamous; cell carcinoma; squamous cell; proliferation ... See more keywords
Role of fibulin-1 gene promoter methylation in the carcinogenesis and development of tongue squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"
DOI: 10.1016/j.oooo.2021.10.006
Abstract: Abstract Objective Recently, fibulin-1 (FBLN1) has been shown to be downregulated in various cancers via promoter hypermethylation. Our study aimed to determine the expression and methylation status of FBLN1 in tongue squamous cell carcinoma (TSCC)… read more here.
Keywords: tongue squamous; methylation; tscc; squamous cell ... See more keywords
Deep convolutional neural networks for tongue squamous cell carcinoma classification using Raman spectroscopy.
Sign Up to like & getrecommendations! Published in 2019 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2019.05.008
Abstract: With deep convolutional neural networks and fiber optic Raman spectroscopy, this study presents a novel classification method that discriminates tongue squamous cell carcinoma (TSCC) from non-tumorous tissue. To achieve this purpose, 24 tissues spectral data… read more here.
Keywords: tongue squamous; classification; squamous cell; deep convolutional ... See more keywords
Role of plasminogen activator inhibitor-1 in oral tongue squamous cell carcinoma: An immunohistochemical and in vitro analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2021.104722
Abstract: OBJECTIVE To evaluate the influence of plasminogen activator inhibitor-1 (PAI-1) on the biological behavior and prognosis of oral tongue squamous cell carcinoma (OTSCC). METHODS Immunoexpression of PAI-1 was analyzed in 60 OTSCC specimens and classified… read more here.
Keywords: tongue squamous; oral tongue; activator inhibitor; expression ... See more keywords
Prognostic biomarkers for oral tongue squamous cell carcinoma: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Cancer"
DOI: 10.1038/bjc.2017.244
Abstract: Background:Identifying informative prognostic biomarkers for oral tongue squamous cell carcinoma (OTSCC) is of great importance in order to better predict tumour behaviour and to guide treatment planning. Here, we summarise existing evidence regarding immunohistochemical prognostic… read more here.
Keywords: tongue squamous; oral tongue; analysis; squamous cell ... See more keywords