Report and Application of a Tool Compound Data Set
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Chemical Information and Modeling"
DOI: 10.1021/acs.jcim.7b00343
Abstract: Small molecule tool compounds have enabled profound advances in life science research. These chemicals are potent, cell active, and selective, and, thus, are suitable for interrogating biological processes. For these chemicals to be useful they… read more here.
Keywords: tool compound; tool; report application; data set ... See more keywords
ZY12201, A Potent TGR5 Agonist: Identification of a Novel Pan CYP450 Inhibitor Tool Compound for In-Vitro Assessment.
Sign Up to like & getrecommendations! Published in 2022 at "Drug metabolism letters"
DOI: 10.2174/1872312815666220315145945
Abstract: BACKGROUND Identification of clinical drug-drug interaction (DDI) risk is an important aspect of drug discovery and development owing to poly-pharmacy in present-day clinical therapy. Drug metabolizing enzymes (DME) plays important role in the efficacy and… read more here.
Keywords: inhibition; cyp; zy12201; tool compound ... See more keywords