Dose Number as a Tool to Guide Lead Optimization for Orally Bioavailable Compounds in Drug Discovery.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01687
Abstract: Small molecule developability challenges have been well documented over the last two decades. One of these critical developability parameters is aqueous solubility. In general, more soluble compounds have improved oral absorption. While enabling formulation technologies… read more here.
Keywords: number tool; dose number; tool guide; discovery ... See more keywords
Evidence maps: a tool to guide research agenda setting
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Evidence-Based Medicine"
DOI: 10.1136/bmjebm-2018-111137
Abstract: A surprisingly huge proportion of medical research still shows poor quality in design, conduct and analysis, leading to far from optimal robustness of findings and validity of conclusions. Research waste remains a problem caused by… read more here.
Keywords: research; evidence maps; tool guide; evidence ... See more keywords
A Tool to Guide Creation of Products for Risk Communications and Community Engagement (RCCE)
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2022.810929
Abstract: Using best practices to produce creative, relatable, contextualized health messaging contributes to effective risk communication. During emergency disasters, the landscape of mis- and dis-information demands strategic, collaborative approaches across all stakeholders particularly government and the… read more here.
Keywords: health; tool guide; rcce; risk communications ... See more keywords