Articles with "tooth development" as a keyword



Differences in Tooth Development in Patients With Unilateral Cleft Lip and Palate

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Published in 2025 at "Clinical and Experimental Dental Research"

DOI: 10.1002/cre2.70086

Abstract: The aim of this study was to investigate tooth development in patients with unilateral cleft lip and palate (UCLP) and unilateral cleft lip and alveolus (UCLA). read more here.

Keywords: development patients; tooth development; cleft lip; patients unilateral ... See more keywords

Epiprofin Regulates Enamel Formation and Tooth Morphogenesis by Controlling Epithelial‐Mesenchymal Interactions During Tooth Development

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Published in 2017 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.3024

Abstract: The synchronization of cell proliferation and cytodifferentiation between dental epithelial and mesenchymal cells is required for the morphogenesis of teeth with the correct functional shapes and optimum sizes. Epiprofin (Epfn), a transcription factor belonging to… read more here.

Keywords: morphogenesis; epithelial mesenchymal; tooth development; dental epithelial ... See more keywords
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Parathyroid hormone‐related peptide (1–34) promotes tooth eruption and inhibits osteogenesis of dental follicle cells during tooth development

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Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.27857

Abstract: Dental follicle cells (DFCs) activate and recruit osteoclasts for tooth development and tooth eruption, whereas DFCs themselves differentiate into osteoblasts to form alveolar bone surrounding tooth roots through the interaction with Hertwig's epithelial root sheath… read more here.

Keywords: eruption; tooth eruption; dfcs; tooth development ... See more keywords
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The role of O-GlcNAcylation mediated by OGT during tooth development.

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Published in 2023 at "Journal of cellular physiology"

DOI: 10.1002/jcp.31024

Abstract: To understand the mechanisms underlying tooth morphogenesis, we examined the developmental roles of important posttranslational modification, O-GlcNAcylation, which regulates protein stability and activity by the addition and removal of a single sugar (O-GlcNAc) to the… read more here.

Keywords: morphogenesis; physiology; tooth development; stage ... See more keywords

Expression of CPNE7 during mouse dentinogenesis

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Published in 2019 at "Journal of Molecular Histology"

DOI: 10.1007/s10735-019-09816-0

Abstract: Interactions between the ectodermal and mesenchymal tissues are the basis of the central mechanism regulating tooth development. Based on this epithelial-mesenchymal interaction (EMI), we demonstrated that copine-7 (CPNE7) is secreted by preameloblasts and regulates the… read more here.

Keywords: cpne7; cpne7 mouse; tooth development; expression ... See more keywords

Role of GATA binding protein 4 (GATA4) in the regulation of tooth development via GNAI3

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-01689-1

Abstract: Transcription factor GATA4 regulates cardiac and osteoblast differentiation. However, its role in tooth development is not clear. Therefore, we generated Wnt1-Cre;GATA4fl/fl mice, with conditional inactivation of the GATA4 gene in the dental papilla mesenchymal cells.… read more here.

Keywords: protein; root; tooth development; role ... See more keywords

Dentinogenesis and Tooth-Alveolar Bone Complex Defects in BMP9/GDF2 Knockout Mice

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Published in 2019 at "Stem Cells and Development"

DOI: 10.1089/scd.2018.0230

Abstract: Tooth development is regulated by sequential and reciprocal epithelium-mesenchymal interactions and their related molecular signaling pathways, such as bone morphogenetic proteins (BMPs). Among the 14 types of BMPs, BMP9 (also known as growth differentiation factor… read more here.

Keywords: bone; tooth development; mice; dentinogenesis ... See more keywords

The significant role of glycosaminoglycans in tooth development

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Published in 2024 at "Glycobiology"

DOI: 10.1093/glycob/cwae024

Abstract: Abstract This review delves into the roles of glycosaminoglycans (GAGs), integral components of proteoglycans, in tooth development. Proteoglycans consist of a core protein linked to GAG chains, comprised of repeating disaccharide units. GAGs are classified… read more here.

Keywords: significant role; tooth development; role glycosaminoglycans; sulfate ... See more keywords

Tooth Development Prediction Using a Generative Machine Learning Approach

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Published in 2024 at "IEEE Access"

DOI: 10.1109/access.2024.3416748

Abstract: This study pioneers the use of generative deep learning in pediatric dentistry to predict dental growth using panoramic radiography, going beyond numerical analysis and providing dynamic representations of tooth development. We employed StyleGAN-XL, a state-of-the-art… read more here.

Keywords: development prediction; tooth development; dentition; dental development ... See more keywords

p75NTR Promotes Circadian-Driven Mineralization During Tooth Development via CK2/PER2 Pathway.

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Published in 2025 at "Cell proliferation"

DOI: 10.1111/cpr.70140

Abstract: Circadian rhythm is an essential biological process that synchronises physiological activities with environmental light/dark cycles. However, its regulatory mechanisms in tooth development remain incompletely understood. Here, we investigated the role of the p75 neurotrophin receptor… read more here.

Keywords: ck2; mineralization tooth; tooth development; mineralization ... See more keywords

Mesenchymal Condensation in Tooth Development and Regeneration: a Focus on Translational Aspects of Organogenesis.

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Published in 2023 at "Physiological reviews"

DOI: 10.1152/physrev.00019.2022

Abstract: The teeth are vertebrate-specific and highly specialized organs performing fundamental functions of mastication and speech, the maintenance of which is crucial for orofacial homeostasis and is further linked to systemic health and human psychosocial well-being.… read more here.

Keywords: regeneration; condensation; condensation tooth; mesenchymal condensation ... See more keywords