Epiprofin Regulates Enamel Formation and Tooth Morphogenesis by Controlling Epithelial‐Mesenchymal Interactions During Tooth Development
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3024
Abstract: The synchronization of cell proliferation and cytodifferentiation between dental epithelial and mesenchymal cells is required for the morphogenesis of teeth with the correct functional shapes and optimum sizes. Epiprofin (Epfn), a transcription factor belonging to… read more here.
Keywords: morphogenesis; epithelial mesenchymal; tooth development; dental epithelial ... See more keywords
Parathyroid hormone‐related peptide (1–34) promotes tooth eruption and inhibits osteogenesis of dental follicle cells during tooth development
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27857
Abstract: Dental follicle cells (DFCs) activate and recruit osteoclasts for tooth development and tooth eruption, whereas DFCs themselves differentiate into osteoblasts to form alveolar bone surrounding tooth roots through the interaction with Hertwig's epithelial root sheath… read more here.
Keywords: eruption; tooth eruption; dfcs; tooth development ... See more keywords
The role of O-GlcNAcylation mediated by OGT during tooth development.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular physiology"
DOI: 10.1002/jcp.31024
Abstract: To understand the mechanisms underlying tooth morphogenesis, we examined the developmental roles of important posttranslational modification, O-GlcNAcylation, which regulates protein stability and activity by the addition and removal of a single sugar (O-GlcNAc) to the… read more here.
Keywords: morphogenesis; physiology; tooth development; stage ... See more keywords
Expression of CPNE7 during mouse dentinogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Histology"
DOI: 10.1007/s10735-019-09816-0
Abstract: Interactions between the ectodermal and mesenchymal tissues are the basis of the central mechanism regulating tooth development. Based on this epithelial-mesenchymal interaction (EMI), we demonstrated that copine-7 (CPNE7) is secreted by preameloblasts and regulates the… read more here.
Keywords: cpne7; cpne7 mouse; tooth development; expression ... See more keywords
Role of GATA binding protein 4 (GATA4) in the regulation of tooth development via GNAI3
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-01689-1
Abstract: Transcription factor GATA4 regulates cardiac and osteoblast differentiation. However, its role in tooth development is not clear. Therefore, we generated Wnt1-Cre;GATA4fl/fl mice, with conditional inactivation of the GATA4 gene in the dental papilla mesenchymal cells.… read more here.
Keywords: protein; root; tooth development; role ... See more keywords
Dentinogenesis and Tooth-Alveolar Bone Complex Defects in BMP9/GDF2 Knockout Mice
Sign Up to like & getrecommendations! Published in 2019 at "Stem Cells and Development"
DOI: 10.1089/scd.2018.0230
Abstract: Tooth development is regulated by sequential and reciprocal epithelium-mesenchymal interactions and their related molecular signaling pathways, such as bone morphogenetic proteins (BMPs). Among the 14 types of BMPs, BMP9 (also known as growth differentiation factor… read more here.
Keywords: bone; tooth development; mice; dentinogenesis ... See more keywords
Mesenchymal Condensation in Tooth Development and Regeneration: a Focus on Translational Aspects of Organogenesis.
Sign Up to like & getrecommendations! Published in 2023 at "Physiological reviews"
DOI: 10.1152/physrev.00019.2022
Abstract: The teeth are vertebrate-specific and highly specialized organs performing fundamental functions of mastication and speech, the maintenance of which is crucial for orofacial homeostasis and is further linked to systemic health and human psychosocial well-being.… read more here.
Keywords: regeneration; condensation; condensation tooth; mesenchymal condensation ... See more keywords
Temporal Control of WNT Activity Regulates Tooth Number in Fish
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Dental Research"
DOI: 10.1177/0022034518811322
Abstract: Wnts determine cell polarity, cell proliferation, and cell differentiation during embryogenesis and play an essential role during tooth development initiation and morphogenesis. Wnt/β-catenin signaling has a time-dependent role in development because various signaling molecules that… read more here.
Keywords: wnt catenin; catenin signaling; tooth development; development ... See more keywords
MSX1 Drives Tooth Morphogenesis Through Controlling Wnt Signaling Activity
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Dental Research"
DOI: 10.1177/00220345211070583
Abstract: Tooth agenesis is a common structural birth defect in humans that results from failure of morphogenesis during early tooth development. The homeobox transcription factor Msx1 and the canonical Wnt signaling pathway are essential for “bud… read more here.
Keywords: morphogenesis; dkk2; tooth development; wnt signaling ... See more keywords
Effects of oncological treatment on tooth development in children with brain tumors: Description of cases
Sign Up to like & getrecommendations! Published in 2017 at "Dental and Medical Problems"
DOI: 10.17219/dmp/74642
Abstract: Despite the fact that the results of oncological treatment improved significantly, cancer remains the main cause of death among children in Poland. Cancer survivors in Łódź have been included in a special preventive program for… read more here.
Keywords: development children; treatment; oncological treatment; tooth development ... See more keywords
The Critical Role of MMP13 in Regulating Tooth Development and Reactionary Dentinogenesis Repair Through the Wnt Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.883266
Abstract: Matrix-metalloproteinase-13 (MMP13) is important for bone formation and remodeling; however, its role in tooth development remains unknown. To investigate this, MMP13-knockout (Mmp13 −/− ) mice were used to analyze phenotypic changes in the dentin–pulp complex,… read more here.
Keywords: mmp13; signaling pathway; expression; tooth development ... See more keywords