Top-"Double-Down" Mass Spectrometry of Histone H4 Proteoforms: Tandem Ultraviolet-Photon and Mobility/Mass-Selected Electron Capture Dissociations.
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DOI: 10.1021/acs.analchem.2c03147
Abstract: Post-translational modifications (PTMs) on intact histones play a major role in regulating chromatin dynamics and influence biological processes such as DNA transcription, replication, and repair. The nature and position of each histone PTM is crucial… read more here.
Keywords: histone; top double; ecd; mobility mass ... See more keywords