Modeling Lower-Order Statistics to Enable Decoy-Free FDR Estimation in Proteomics.
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DOI: 10.1021/acs.jproteome.2c00604
Abstract: One of the chief objectives in mass spectrometry-based peptide identification in proteomics is the statistical validation of top-scoring peptide-spectrum matches (PSMs) in the form of false discovery rate (FDR) estimation. Existing methods construct a null… read more here.
Keywords: fdr estimation; lower order; top scoring; estimation ... See more keywords