Untangling the roles of TOP2A and TOP2B in transcription and cancer
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DOI: 10.1126/sciadv.add4920
Abstract: Type II topoisomerases (TOP2) are conserved regulators of chromatin topology that catalyze reversible DNA double-strand breaks (DSBs) and are essential for maintaining genomic integrity in diverse dynamic processes such as transcription, replication, and cell division.… read more here.
Keywords: topology; top2a top2b; transcription; untangling roles ... See more keywords