Smc5/6 functions with Sgs1-Top3-Rmi1 to complete chromosome replication at natural pause sites
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-22217-w
Abstract: Smc5/6 is essential for genome structural integrity by yet unknown mechanisms. Here we find that Smc5/6 co-localizes with the DNA crossed-strand processing complex Sgs1-Top3-Rmi1 (STR) at genomic regions known as natural pausing sites (NPSs) where… read more here.
Keywords: top3 rmi1; smc5 functions; sgs1 top3; replication ... See more keywords
Unresolved Recombination Intermediates Cause a RAD9-Dependent Cell Cycle Arrest in Saccharomyces cerevisiae
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DOI: 10.1534/genetics.119.302632
Abstract: It has been suggested that the conserved Sgs1-Top3-Rmi1 (STR) helicasedecatenase complex resolves double Holliday junction recombination intermediates (dHJs) as noncrossovers by a process called dissolution. Lichten, Kaur, and GN tested this by accumulating dHJs during… read more here.
Keywords: top3 rmi1; recombination; cell cycle; recombination intermediates ... See more keywords