A dual-activity topoisomerase complex promotes both transcriptional activation and repression in response to starvation.
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DOI: 10.1093/nar/gkad086
Abstract: Topoisomerases are required to release topological stress generated by RNA polymerase II (RNAPII) during transcription. Here, we show that in response to starvation, the complex of topoisomerase 3b (TOP3B) and TDRD3 can enhance not only… read more here.
Keywords: top3b; transcriptional activation; topoisomerase; top3b tdrd3 ... See more keywords