Topical administration of DPP-IV inhibitors prevents retinal neurodegeneration in experimental diabetes
Sign Up to like & getrecommendations! Published in 2017 at "Diabetologia"
DOI: 10.1007/s00125-017-4388-y
Abstract: Aims/hypothesisThe main aims of the present study were: (1) to assess the expression and content of dipeptidyl peptidase IV (DPP-IV) in human and db/db mouse retinas, and in human vitreous fluid; and (2) to determine… read more here.
Keywords: topical administration; glp; neurodegeneration; dpp ... See more keywords
Topical administration of pullulan gel accelerates skin tissue regeneration by enhancing collagen synthesis and wound contraction in rats
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Biological Macromolecules"
DOI: 10.1016/j.ijbiomac.2020.01.187
Abstract: Abstract Here, we have studied the efficacy of pullulan gel on wound healing by performing biochemical, biophysical and histological investigations. A 2 cm2 open excision wound was made on the dorsum of the rats and topically… read more here.
Keywords: pullulan gel; administration pullulan; pullulan; gel accelerates ... See more keywords
In vivo assessing colitis severity by topical administration of fluorescent probe against neutrophils.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2021.122519
Abstract: Inflammatory bowel disease has become a global burden given its high incidence and refractory to medical treatment. Improved diagnostic strategies to monitor disease activity more accurately are necessary to conduct and evaluate medical treatment. High… read more here.
Keywords: topical administration; probe; cpm; colitis severity ... See more keywords
Safety and Efficacy of Topical Administration of Tranexamic Acid in High-Risk Patients Undergoing Posterior Lumbar Interbody Fusion Surgery.
Sign Up to like & getrecommendations! Published in 2021 at "World neurosurgery"
DOI: 10.1016/j.wneu.2021.04.088
Abstract: OBJECTIVE To evaluate the safety and efficacy of topical administration of tranexamic acid (TXA) in high-risk patients undergoing posterior lumbar interbody fusion (PLIF) surgery METHODS: In this single-center, retrospective cohort study, a total of 120… read more here.
Keywords: surgery; risk; topical administration; high risk ... See more keywords
Skin penetration and tissue permeation after topical administration of diclofenac
Sign Up to like & getrecommendations! Published in 2017 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2017.1352497
Abstract: Abstract Objective: Topical delivery of drugs is an alternative to oral administration, often with similar efficacy but potentially a more favorable tolerability profile. However, topical formulations need to be able to penetrate the skin and… read more here.
Keywords: administration; topical administration; diclofenac; penetration tissue ... See more keywords
VITREOUS PROSTAGLANDIN E2 CHANGES AFTER TOPICAL ADMINISTRATION OF DICLOFENAC 0.1%, INDOMETHACIN 0.5%, NEPAFENAC 0.3%, AND BROMFENAC 0.09.
Sign Up to like & getrecommendations! Published in 2019 at "Retina"
DOI: 10.1097/iae.0000000000002674
Abstract: PURPOSE To evaluate the vitreous concentration of different nonsteroidal anti-inflammatory drugs (NSAIDs) after topical administration and the related prostaglandin E2 (PGE2) levels in patients undergoing pars plana vitrectomy. METHODS A prospective, randomized, investigator-masked study was… read more here.
Keywords: diclofenac indomethacin; bromfenac; indomethacin nepafenac; pge2 levels ... See more keywords
Delirium caused by topical administration of cyclopentolate for cataract surgery in mild cognitive impairment due to Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2021 at "Medicine"
DOI: 10.1097/md.0000000000024394
Abstract: Abstract Rationales: Cholinergic modification by anticholinergic medication can produce adverse effects in central nervous system (CNS) and cyclopentolate is an antimuscarinic agent widely used for ophthalmologic management. We demonstrate a rare case of hyperactive delirium… read more here.
Keywords: cyclopentolate; administration cyclopentolate; surgery; delirium ... See more keywords
Anti‐inflammatory effect of amygdalin analogs following topical administration on the TPA‐induced irritant contact dermatitis model in mice
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Dermatology"
DOI: 10.1111/exd.14284
Abstract: In vitro studies on keratinocytes demonstrate the effect of amygdalin analogs as inflammation modulators, downregulating pro-inflammatory cytokines with the concomitant upregulation of anti-inflammatory ones. They are also effective in reducing psoriatic lesions, as shown in… read more here.
Keywords: anti inflammatory; topical administration; amygdalin analogs; tpa induced ... See more keywords
The pharmacokinetics of moxidectin following intravenous and topical administration to swine.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of veterinary pharmacology and therapeutics"
DOI: 10.1111/jvp.12693
Abstract: The pharmacokinetic parameters of moxidectin (MXD) after intravenous and pour-on (topical) administration were studied in sixteen pigs at a single dose of 1.25 and 2.5 mg/kg BW (body weight), respectively. Blood samples were collected at pretreatment… read more here.
Keywords: moxidectin following; administration; topical administration; pharmacokinetics moxidectin ... See more keywords
Intravenous Combined with Topical Administration of Tranexamic Acid in Primary Total Hip Arthroplasty: A Randomized Controlled Trial
Sign Up to like & getrecommendations! Published in 2017 at "Orthopaedic Surgery"
DOI: 10.1111/os.12287
Abstract: Although there are still some controversies, large previous studies have confirmed that intravenous (i.v.) tranexamic acid (TXA) can effectively reduce blood loss and transfusions in total hip arthroplasty (THA) without increasing the risk of deep… read more here.
Keywords: topical administration; combined topical; tranexamic acid; hip arthroplasty ... See more keywords
Comparative Analysis of the Effectiveness of the Topical Administration of Benzocaine and EMLA® on Oral Pain and Tactile Sensitivity
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Dentistry"
DOI: 10.1155/2018/7916274
Abstract: Objectives To compare the effectiveness of the topical administration of benzocaine and EMLA on oral pain and tactile sensitivity. Materials and Methods A randomized, double-blind, split-mouth clinical trial was carried out with 20 volunteers. The… read more here.
Keywords: administration benzocaine; topical administration; sensitivity; effectiveness topical ... See more keywords