Articles with "topical application" as a keyword



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Effects of topical application of tramadol with/without dexmedetomidine and proparacaine on corneal sensitivity in rats

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Published in 2020 at "International Ophthalmology"

DOI: 10.1007/s10792-020-01596-x

Abstract: To evaluate the corneal anesthetic effect following topical application of tramadol alone and in combination with dexmedetomidine, and compare it to proparacaine, in clinically healthy rats. A randomized, crossover study was performed. Twenty Wistar albino… read more here.

Keywords: topical application; corneal; tramadol; dexmedetomidine ... See more keywords
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Topical application of metformin accelerates cutaneous wound healing in streptozotocin-induced diabetic rats.

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Published in 2021 at "Molecular biology reports"

DOI: 10.1007/s11033-021-06843-7

Abstract: BACKGROUND Diabetic chronic wound, which is one of the diabetic complications caused by hyperglycemia, characterized by prolonged inflammation has become one of the most serious challenges in the clinic. Hyperglycemia during diabetes not only causes… read more here.

Keywords: topical application; wound healing; metformin; diabetic rats ... See more keywords
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Topical application of Hydroxysafflor Yellow A accelerates the wound healing in streptozotocin induced T1DM rats

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Published in 2018 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2018.01.018

Abstract: Abstract To investigate the effects of Hydroxysafflor Yellow A (HSYA), which is derived from safflower, on the proliferation, migration and angiogenesis of cells in vitro and its potential efficacy in vivo when topically applied to… read more here.

Keywords: topical application; wound healing; hsya; hydroxysafflor yellow ... See more keywords
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Nanodelivery System Alters an Insect Growth Regulator's Action Mode: From Oral Feeding to Topical Application.

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Published in 2022 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.2c08239

Abstract: Insect growth regulators (IGRs) guide animal development through injection, oral feeding, or topical application. Among them, lufenuron is a widely used insect cuticle inhibitor but only shows a gastric toxic effect. Lacking contact toxicity limits… read more here.

Keywords: application; topical application; contact toxicity; feeding topical ... See more keywords
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Supramolecular gels from sugar-linked triazole amphiphiles for drug entrapment and release for topical application

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Published in 2019 at "RSC Advances"

DOI: 10.1039/c9ra02868d

Abstract: Spontaneous formation of hierarchical supramolecular gels show solvent dictated self-assembly and spatio-temporal positioning of drug molecules in the network accounting for differential release profiles for topical application. read more here.

Keywords: drug; gels sugar; topical application; release ... See more keywords
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Immediate‐type allergic and protease‐mediated reactions are involved in scratching behaviour induced by topical application of Dermatophagoides farinae extract in NC/Nga mice

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Published in 2018 at "Experimental Dermatology"

DOI: 10.1111/exd.13322

Abstract: Atopic dermatitis (AD)‐like dermatitis can be induced by repeated topical application of an ointment containing Dermatophagoides farinae body (Dfb) extract in NC/Nga mice. This AD‐like murine model also exhibits a biphasic increase in the number… read more here.

Keywords: topical application; dermatophagoides farinae; application; nga mice ... See more keywords
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In vitro human skin concentrations following topical application of 2% tranexamic acid in co‐enhancer cream and branded cream formulations

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Published in 2020 at "Journal of Cosmetic Dermatology"

DOI: 10.1111/jocd.13301

Abstract: Melasma is a common pigmentary disorder that responds well to treatment with oral and/or locally injected tranexamic acid but less so to topical application. We hypothesized that this may be due to an inability of… read more here.

Keywords: topical application; vitro human; tranexamic acid; cream ... See more keywords
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Topical application of a commercially available formulation of vitamin C stabilized by vitamin E and ferulic acid reduces tissue viability and protein synthesis in ex vivo human normal skin

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Published in 2020 at "Journal of Cosmetic Dermatology"

DOI: 10.1111/jocd.13413

Abstract: Aqueous formulations of vitamin C stabilized by vitamin E and ferulic acid at low pH effectively protect skin against reactive oxygen species‐induced damage. However, the effects of these formulations on human skin have not clearly… read more here.

Keywords: topical application; vitamin ferulic; vitamin stabilized; stabilized vitamin ... See more keywords
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Microbotox injection versus its topical application following microneedling in the treatment of wide facial pores: A split face comparative study

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Published in 2023 at "Journal of Cosmetic Dermatology"

DOI: 10.1111/jocd.15590

Abstract: Enlarged facial pores and seborrhea are common cosmetic problems. Mesobotox has been proved to be effective safe therapeutic option. read more here.

Keywords: topical application; microbotox injection; facial pores; versus topical ... See more keywords
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Corneal anesthesia associated with topical application of 2% lidocaine nonophthalmic gel to healthy canine eyes.

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Published in 2020 at "Veterinary ophthalmology"

DOI: 10.1111/vop.12757

Abstract: OBJECTIVE To assess the degree and duration of corneal anesthesia induced by topical application of 2% lidocaine gel to the healthy canine eye. ANIMALS Nineteen adult Beagles free of ocular abnormalities. PROCEDURES Baseline corneal touch… read more here.

Keywords: topical application; application lidocaine; lidocaine; gel ... See more keywords
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Safety and efficacy of unilateral topical application of rocuronium bromide in healthy scops owls (Otus scops).

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Published in 2021 at "Veterinary ophthalmology"

DOI: 10.1111/vop.12856

Abstract: OBJECTIVE To evaluate the safety and efficacy of unilateral topical application of rocuronium bromide in scops owls. ANIMALS STUDIED Ten healthy adult scops owls. PROCEDURES Birds weighting between 82-111 g were enrolled. Complete physical and ophthalmic… read more here.

Keywords: topical application; safety efficacy; scops owls; rocuronium bromide ... See more keywords