Effects of topical application of tramadol with/without dexmedetomidine and proparacaine on corneal sensitivity in rats
Sign Up to like & getrecommendations! Published in 2020 at "International Ophthalmology"
DOI: 10.1007/s10792-020-01596-x
Abstract: To evaluate the corneal anesthetic effect following topical application of tramadol alone and in combination with dexmedetomidine, and compare it to proparacaine, in clinically healthy rats. A randomized, crossover study was performed. Twenty Wistar albino… read more here.
Keywords: topical application; corneal; tramadol; dexmedetomidine ... See more keywords
Topical application of metformin accelerates cutaneous wound healing in streptozotocin-induced diabetic rats.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06843-7
Abstract: BACKGROUND Diabetic chronic wound, which is one of the diabetic complications caused by hyperglycemia, characterized by prolonged inflammation has become one of the most serious challenges in the clinic. Hyperglycemia during diabetes not only causes… read more here.
Keywords: topical application; wound healing; metformin; diabetic rats ... See more keywords
Topical application of Hydroxysafflor Yellow A accelerates the wound healing in streptozotocin induced T1DM rats
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.01.018
Abstract: Abstract To investigate the effects of Hydroxysafflor Yellow A (HSYA), which is derived from safflower, on the proliferation, migration and angiogenesis of cells in vitro and its potential efficacy in vivo when topically applied to… read more here.
Keywords: topical application; wound healing; hsya; hydroxysafflor yellow ... See more keywords
Nanodelivery System Alters an Insect Growth Regulator's Action Mode: From Oral Feeding to Topical Application.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c08239
Abstract: Insect growth regulators (IGRs) guide animal development through injection, oral feeding, or topical application. Among them, lufenuron is a widely used insect cuticle inhibitor but only shows a gastric toxic effect. Lacking contact toxicity limits… read more here.
Keywords: application; topical application; contact toxicity; feeding topical ... See more keywords
Topical application of the HSP90 inhibitor 17-AAG reduces skin inflammation and partially restores microbial balance: implications for atopic dermatitis therapy
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-05307-3
Abstract: Heat shock proteins belonging to the HSP90 family promote inflammation and are potential therapeutic targets in inflammatory and autoimmune diseases. Here the effects of the HSP90 inhibitor 17-AAG applied topically were evaluated in a DNCB-induced… read more here.
Keywords: hsp90 inhibitor; topical application; aag; inhibitor aag ... See more keywords
Supramolecular gels from sugar-linked triazole amphiphiles for drug entrapment and release for topical application
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra02868d
Abstract: Spontaneous formation of hierarchical supramolecular gels show solvent dictated self-assembly and spatio-temporal positioning of drug molecules in the network accounting for differential release profiles for topical application. read more here.
Keywords: drug; gels sugar; topical application; release ... See more keywords
Topical Application of TT-10 Ameliorates Impaired Wound Healing
Sign Up to like & getrecommendations! Published in 2024 at "Plastic and Reconstructive Surgery"
DOI: 10.1097/prs.0000000000011492
Abstract: Background: In recent decades, chronic wounds have become an increasingly significant clinical concern because of their increasing morbidity and socioeconomic toll. However, there is currently no product available on the market that specifically targets this… read more here.
Keywords: topical application; chronic wounds; yap; yap activity ... See more keywords
Immediate‐type allergic and protease‐mediated reactions are involved in scratching behaviour induced by topical application of Dermatophagoides farinae extract in NC/Nga mice
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Dermatology"
DOI: 10.1111/exd.13322
Abstract: Atopic dermatitis (AD)‐like dermatitis can be induced by repeated topical application of an ointment containing Dermatophagoides farinae body (Dfb) extract in NC/Nga mice. This AD‐like murine model also exhibits a biphasic increase in the number… read more here.
Keywords: topical application; dermatophagoides farinae; application; nga mice ... See more keywords
In vitro human skin concentrations following topical application of 2% tranexamic acid in co‐enhancer cream and branded cream formulations
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.13301
Abstract: Melasma is a common pigmentary disorder that responds well to treatment with oral and/or locally injected tranexamic acid but less so to topical application. We hypothesized that this may be due to an inability of… read more here.
Keywords: topical application; vitro human; tranexamic acid; cream ... See more keywords
Topical application of a commercially available formulation of vitamin C stabilized by vitamin E and ferulic acid reduces tissue viability and protein synthesis in ex vivo human normal skin
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.13413
Abstract: Aqueous formulations of vitamin C stabilized by vitamin E and ferulic acid at low pH effectively protect skin against reactive oxygen species‐induced damage. However, the effects of these formulations on human skin have not clearly… read more here.
Keywords: topical application; vitamin ferulic; vitamin stabilized; stabilized vitamin ... See more keywords
Microbotox injection versus its topical application following microneedling in the treatment of wide facial pores: A split face comparative study
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.15590
Abstract: Enlarged facial pores and seborrhea are common cosmetic problems. Mesobotox has been proved to be effective safe therapeutic option. read more here.
Keywords: topical application; microbotox injection; facial pores; versus topical ... See more keywords