DNA topoisomerase II alpha promotes the metastatic characteristics of glioma cells by transcriptionally activating β-catenin
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DOI: 10.1080/21655979.2021.2023985
Abstract: ABSTRACT DNA topoisomerase II alpha (TOP2A) reportedly plays a crucial role in several cancers, however, the precise regulatory role of TOP2A in metastatic characteristics of glioma is still poorly understood. Herein, we sought to elucidate… read more here.
Keywords: topoisomerase alpha; top2a; characteristics glioma; dna topoisomerase ... See more keywords
Ciclopirox Olamine Exerts Tumor-Suppressor Effects via Topoisomerase II Alpha in Lung Adenocarcinoma
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DOI: 10.3389/fonc.2022.791916
Abstract: Background Globally, lung cancer is one of the most malignant tumors, of which lung adenocarcinoma (LUAD) is the most common subtype, with a particularly poor prognosis. Ciclopirox olamine (CPX) is an antifungal drug and was… read more here.
Keywords: luad; topoisomerase alpha; suppressor effects; ciclopirox olamine ... See more keywords