Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states
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DOI: 10.1038/s41467-021-27686-7
Abstract: Eukaryotic topoisomerases I (TOP1) are ubiquitous enzymes removing DNA torsional stress. However, there is little data concerning the three-dimensional structure of TOP1 in the absence of DNA, nor how the DNA molecule can enter/exit its… read more here.
Keywords: dna; open closed; conformation; topoisomerase top1 ... See more keywords