Articles with "topological relationships" as a keyword



Mining Relationships among Multiple Entities in Biological Networks

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Published in 2020 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"

DOI: 10.1109/tcbb.2019.2904965

Abstract: Identifying topological relationships among multiple entities in biological networks is critical towards the understanding of the organizational principles of network functionality. Theoretically, this problem can be solved using minimum Steiner tree (MSTT) algorithms. However, due… read more here.

Keywords: among multiple; topological relationships; relationships among; biological networks ... See more keywords

Accurate prediction of drug-protein interactions by maintaining the original topological relationships among embeddings

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Published in 2025 at "BMC Biology"

DOI: 10.1186/s12915-025-02338-0

Abstract: Learning-based methods have recently demonstrated strong potential in predicting drug-protein interactions (DPIs). However, existing approaches often fail to achieve accurate predictions on real-world imbalanced datasets while maintaining high generalizability and scalability, limiting their practical applicability.… read more here.

Keywords: protein interactions; drug; topological relationships; relationships among ... See more keywords