Articles with "topovectorial mechanisms" as a keyword



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Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N‐terminal polypeptides during maturation of the CNC‐bZIP factor

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Published in 2018 at "Toxicology and Applied Pharmacology"

DOI: 10.1016/j.taap.2018.09.039

Abstract: &NA; The topobiological behaviour of Nrf1 dictates its post‐translational modification and its ability to transactivate target genes. Here, we have elucidated that topovectorial mechanisms control the juxtamembrane processing of Nrf1 on the cyto/nucleoplasmic side of… read more here.

Keywords: topovectorial mechanisms; juxtamembrane; mechanisms control; proteolytic processing ... See more keywords