Toremifene, rather than tamoxifen, might be a better option for the adjuvant endocrine therapy in CYP2D6*10T/T genotype breast cancer patients in China
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31639
Abstract: Toremifene (TOR) is a valid and safe alternative to tamoxifen (TAM) for adjuvant endocrine therapy in breast cancer patients with a metabolic pathway that differs from that of TAM. TOR might have a therapeutic advantage… read more here.
Keywords: genotype; breast cancer; tor; cancer ... See more keywords
Evidence of shape variation in wild Tor Mahseer (Tor tor) from Indian Rivers
Sign Up to like & getrecommendations! Published in 2021 at "River Research and Applications"
DOI: 10.1002/rra.3866
Abstract: It has been hypothesized that geographical isolation between river ecosystems often resulted in phenotypic variation and ultimately change in the population structure of aquatic species. To test the hypothesis, 471 individuals of Tor Mahseer, Tor… read more here.
Keywords: tor; shape; indian rivers; river ... See more keywords
Express yourself: how PP2A-B55Pab1 helps TORC1 talk to TORC2
Sign Up to like & getrecommendations! Published in 2017 at "Current Genetics"
DOI: 10.1007/s00294-017-0721-8
Abstract: The control of cell fate, growth and proliferation in response to nitrogen availability is a tightly controlled process, with the two TOR complexes (TORC1 and TORC2) and their effectors playing a central role. PP2A-B55Pab1 has… read more here.
Keywords: express pp2a; b55pab1 helps; b55pab1; tor ... See more keywords
Control of RNA polymerase II-transcribed genes by direct binding of TOR kinase
Sign Up to like & getrecommendations! Published in 2017 at "Current Genetics"
DOI: 10.1007/s00294-017-0738-z
Abstract: Under conditions of nutrient limitation and cellular stress, or by addition of rapamycin, the mechanistic target of rapamycin complex 1 (mTORC1) is inhibited. This results in downregulation of genes that encode rRNA and ribosomal proteins.… read more here.
Keywords: polymerase transcribed; tor kinase; direct binding; control ... See more keywords
HMGB proteins involved in TOR signaling as general regulators of cell growth by controlling ribosome biogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Current Genetics"
DOI: 10.1007/s00294-018-0842-8
Abstract: The number of ribosomes and their activity need to be highly regulated because their function is crucial for the cell. Ribosome biogenesis is necessary for cell growth and proliferation in accordance with nutrient availability and… read more here.
Keywords: ribosome biogenesis; cell growth; tor; hmgb proteins ... See more keywords
Speech-based takeover requests in conditionally automated driving: Effects of different voices on the driver takeover performance.
Sign Up to like & getrecommendations! Published in 2022 at "Applied ergonomics"
DOI: 10.1016/j.apergo.2022.103695
Abstract: This study explored the possibility of applying personalized takeover requests (TORs) in an automated driving system (ADS), which required drivers to regain control when the system reached its limits. A driving simulator experiment was conducted… read more here.
Keywords: tor; time; automated driving; takeover ... See more keywords
Dietary nucleotides in the diets of on-growing grass carp (Ctenopharyngodon idella) suppress Aeromonas hydrophila induced intestinal inflammation and enhance intestinal disease-resistance via NF-κB and TOR signaling
Sign Up to like & getrecommendations! Published in 2020 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2020.736075
Abstract: Abstract The beneficial influences of nucleotides on fish intestinal immune responses and the mechanisms underlying the regulation of on-growing grass carp (Ctenopharyngodon idella) were evaluated using A. hydrophila induced intestinal inflammation model in vivo. Sixty… read more here.
Keywords: growing grass; grass; grass carp; dietary nucleotides ... See more keywords
AMPK and TOR: The Yin and Yang of Cellular Nutrient Sensing and Growth Control.
Sign Up to like & getrecommendations! Published in 2020 at "Cell metabolism"
DOI: 10.1016/j.cmet.2020.01.015
Abstract: The AMPK (AMP-activated protein kinase) and TOR (target-of-rapamycin) pathways are interlinked, opposing signaling pathways involved in sensing availability of nutrients and energy and regulation of cell growth. AMPK (Yin, or the "dark side") is switched… read more here.
Keywords: ampk tor; growth; growth control; tor ... See more keywords
Characterization of fume composition and rheological properties of asphalt with crumb rubber activated by microwave and TOR
Sign Up to like & getrecommendations! Published in 2017 at "Construction and Building Materials"
DOI: 10.1016/j.conbuildmat.2017.07.199
Abstract: Abstract This paper studied asphalt fume chemical composition, rheological properties and microstructure of asphalt with crumb rubber (CR) activated by microwave and trans-polyoctenamer (TOR). To that end, asphalt fume was trapped through laboratory fume generation… read more here.
Keywords: activated microwave; composition rheological; rheological properties; tor ... See more keywords
Diverse nitrogen signals activate convergent ROP2-TOR signaling in Arabidopsis.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental cell"
DOI: 10.1016/j.devcel.2021.03.022
Abstract: The evolutionarily conserved target-of-rapamycin (TOR) kinase coordinates cellular and organismal growth in all eukaryotes. Amino acids (AAs) are key upstream signals for mammalian TOR activation, but how nitrogen-related nutrients regulate TOR signaling in plants is… read more here.
Keywords: nitrogen; signals activate; tor signaling; diverse nitrogen ... See more keywords
Galactosamine reduces sandfly gut protease activity through TOR downregulation and increases Lutzomyia susceptibility to Leishmania.
Sign Up to like & getrecommendations! Published in 2020 at "Insect biochemistry and molecular biology"
DOI: 10.1016/j.ibmb.2020.103393
Abstract: In sandflies, males and females feed on carbohydrates but females must get a blood meal for egg maturation. Using artificial blood meals, this study aimed to understand how galactosamine interferes with sandfly digestive physiology. We… read more here.
Keywords: galactosamine; physiology; galactosamine reduces; reduces sandfly ... See more keywords