PDIA4 promotes glioblastoma progression via the PI3K/AKT/m-TOR pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2022.01.115
Abstract: Protein disulfide isomerase A4 (PDIA4) is highly expressed in clear cell ovarian carcinoma and lung cancer. Through analysis of TCGA database and CGGA database, we noted that PDIA4 is a key promotor of glioblastoma (GBM).… read more here.
Keywords: akt tor; tor pathway; pi3k akt; pdia4 ... See more keywords
Tombusvirus RNA replication depends on the TOR pathway in yeast and plants.
Sign Up to like & getrecommendations! Published in 2018 at "Virology"
DOI: 10.1016/j.virol.2018.04.010
Abstract: Similar to other (+)RNA viruses, tomato bushy stunt virus (TBSV) utilizes metabolites, lipids, membranes, and co-opted host factors during replication. The coordination of cell metabolism and growth with environmental cues is performed by the target… read more here.
Keywords: tor activity; tor pathway; yeast; tombusvirus replication ... See more keywords
Growing at the right time: interconnecting the TOR pathway with photoperiod and circadian regulation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/erac279
Abstract: To ensure growth responses accurately match the available energy resources, plants integrate external cues (e.g. photoperiod) with metabolic signals (carbon/energy) to coordinate the diel activity of the TOR signalling pathway. read more here.
Keywords: interconnecting tor; growing right; time interconnecting; tor ... See more keywords
Shared Components of the FRQ-Less Oscillator and TOR Pathway Maintain Rhythmicity in Neurospora
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biological Rhythms"
DOI: 10.1177/0748730421999948
Abstract: Molecular models for the endogenous oscillators that drive circadian rhythms in eukaryotes center on rhythmic transcription/translation of a small number of “clock genes.” Although substantial evidence supports the concept that negative and positive transcription/translation feedback… read more here.
Keywords: frq less; rhythmicity; tor pathway; rhythms ... See more keywords
The TOR Pathway Plays Pleiotropic Roles in Growth and Stress Responses of the Fungal Pathogen Cryptococcus neoformans
Sign Up to like & getrecommendations! Published in 2019 at "Genetics"
DOI: 10.1534/genetics.119.302191
Abstract: The target of rapamycin (TOR) pathway is an evolutionarily conserved signal transduction system that governs a plethora of eukaryotic biological processes, but its role in Cryptococcus neoformans remains elusive. In this study, we investigated the… read more here.
Keywords: cryptococcus neoformans; tor pathway; stress; pathway ... See more keywords