TORC1 signaling regulates DNA replication via DNA replication protein levels.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.10.018
Abstract: Accurate DNA replication is at the heart of faithful genome transmission in dividing cells. DNA replication is strictly controlled by various factors. However, how environmental stresses such as nutrient starvation impact on these factors and… read more here.
Keywords: protein; torc1 signaling; dna replication; mcm3 degradation ... See more keywords
Yeast Ataxin-2 Forms an Intracellular Condensate Required for the Inhibition of TORC1 Signaling during Respiratory Growth
Sign Up to like & getrecommendations! Published in 2019 at "Cell"
DOI: 10.1016/j.cell.2019.02.043
Abstract: Yeast ataxin-2, also known as Pbp1 (polyA binding protein-binding protein 1), is an intrinsically disordered protein implicated in stress granule formation, RNA biology, and neurodegenerative disease. To understand the endogenous function of this protein, we… read more here.
Keywords: torc1; torc1 signaling; respiratory growth; yeast ataxin ... See more keywords
The Social Network of TORC1 in plants.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of experimental botany"
DOI: 10.1093/jxb/erac278
Abstract: The Target Of Rapamycin Complex 1 (TORC1) is a highly conserved serine-threonine protein kinase crucial for coordinating growth according to nutrient availability in eukaryotes. TORC1 works as a central integrator of multiple nutrient inputs such… read more here.
Keywords: torc1; network; social network; torc1 signaling ... See more keywords
Anabolic SIRT4 Exerts Retrograde Control over TORC1 Signaling by Glutamine Sparing in the Mitochondria
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00212-19
Abstract: Anabolic and catabolic signaling mediated via mTOR and AMPK (AMP-activated kinase) have to be intrinsically coupled to mitochondrial functions for maintaining homeostasis and mitigate cellular/organismal stress. Although glutamine is known to activate mTOR, whether and… read more here.
Keywords: sirt4; mtor; torc1 signaling; glutamine sparing ... See more keywords
TORC1 Signaling Controls the Stability and Function of α-Arrestins Aly1 and Aly2
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12040533
Abstract: Nutrient supply dictates cell signaling changes, which in turn regulate membrane protein trafficking. To better exploit nutrients, cells relocalize membrane transporters via selective protein trafficking. Key in this reshuffling are the α-arrestins, selective protein trafficking… read more here.
Keywords: protein trafficking; torc1 signaling; aly1 aly2; arrestins aly1 ... See more keywords