Tormentic acid inhibits IL-1β-induced chondrocyte apoptosis by activating the PI3K/Akt signaling pathway.
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DOI: 10.3892/mmr.2018.8425
Abstract: Interleukin-1β (IL-1β) accelerates degradation of the cartilage matrix and induces apoptosis of chondrocytes. Tormentic acid (TA) is a triterpene isolated from the stem bark of the Vochysia divergens plant, which has been demonstrated to exert in vitro… read more here.
Keywords: akt; chondrocyte apoptosis; apoptosis; pi3k akt ... See more keywords