Transition Metal-Catalyzed Biaryl Atropisomer Synthesis via a Torsional Strain Promoted Ring-Opening Reaction.
Sign Up to like & getrecommendations! Published in 2022 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.2c00175
Abstract: ConspectusArising from the restricted rotation of a single bond caused by steric or electronic effects, atropisomerism is one of the few fundamental categories for molecules to manifest their three-dimensional characters into which axially chiral biaryl… read more here.
Keywords: synthesis; torsional strain; ring opening; opening reaction ... See more keywords
Torsional strain inversed chemoselectivity in a Pd-catalyzed atroposelective carbonylation reaction of dibenzothiophenium
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc00341d
Abstract: A palladium-catalyzed enantioselective ring-opening/carbonylation of cyclic diarylsulfonium salts is reported. In comparison to thioethers, the sulfonium salts displayed high reactivity and enabled the reaction to be performed under mild conditions (room temperature). The steric repulsion… read more here.
Keywords: torsional strain; strain inversed; reaction; chemoselectivity catalyzed ... See more keywords